Weeds may be unwanted for a number of reasons: they might be unsightly, or crowd out or restrict light to more desirable plants or use limited nutrients from the soil. They can harbor and spread plant pathogens that infect and degrade the quality of crop or horticultural plants. Some weeds are a nuisance because they have thorns or prickles, some have chemicals that cause skin irritation or are hazardous if eaten, or have parts that come off and attach to fur or clothes.

The term weed in its general sense is a subjective one, without any classification value, since a "weed" is not a weed when growing where it belongs or is wanted. Indeed, a number of "weeds" have been used in gardens or other cultivated-plant settings. An example is the corncockle, Agrostemma, which was a common field weed exported from Europe along with wheat, but now sometimes grown as a garden plant.

Professor Richard C. Lewontin of Harvard University defines weeds as plants that create environmental conditions in which it cannot reproduce. He takes the example of pine trees that crowd out sunlight such that its own offspring cannot grow. Weeds continue to exist, because the environment is continually being disturbed to create open conditions for new generations, such as forest fires and human activity.

Distribution

The weedy nature of these species often gives them an advantage over more desirable crop species because they often grow quickly and reproduce quickly, have seeds that persist in the soil seed bank for many years, or have short lifespans with multiple generations in the same growing season. Perennial weeds often have underground stems that spread out under the soil surface or, like ground ivy (Glechoma hederacea), have creeping stems that root and spread out over the ground. A number of weedy species have developed allelopathy, chemical means to prevent the germination or growth of neighboring plants.

Relation to humans

As long as humans have cultivated plants, weeds have been a problem. Weeds have even been mentioned in religious and literature texts like the following quotes from Genesis and a Shakespearean sonnet:

"Cursed is the ground because of you; through painful toil you will eat of it all the days of your life. It will produce thorns and thistles for you, and you will eat the plants of the field. By the sweat of your brow you will eat your food until you return to the ground,"

"To thy fair flower add the rank smell of weeds: But why thy odour matcheth not thy show, The soil is this, that thou dost common grow."