What we found on the web about Sphingosine
Sphingosine - Wikipedia, the free encyclopedia
Sphingosine (2-amino-4-octadecene-1,3-diol) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell ...
Sphingosine kinase - Wikipedia, the free encyclopedia
Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation Sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine.
sphingosine-1-phosphate - structure, occurrence, biosynthesis and ...
Fatty acids and eicosanoids Simple lipids, etc. Complex glycerolipids Sphingolipids Analysis. Chromatography (GC, HPLC, Ag), mass spectrometry, NMR spectroscopy, etc.
Sphingosine -Echelon Biosciences Inc.
Sphingosine S-1000 Sphingosine, S1000, sphingo, lipid, protein, caramidase, sphingolipids, g-protein, protein inhibitor, shingosine 1-phosphate, s1p Sphingosine S-1000 ...
Sphingosine :: analysis
BioInfoBank Library :: Sphingosine :: analysis :: Quantitative analysis of sphingosine-1-phosphate by HPLC after napthalene-2,3-dicarboxaldehyde (NDA) derivatization. On neutral ...
Spingosine kinases and related products
Active Recombinant Sphingosine Kinase Enzymes . Sphingosine 1-Phosphate Kinase 1 & 2 (Sphk1 & 2) catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP ...
Sphingosine Phosphate Lyase Expression Is Essential for Normal ...
Sphingolipids are ubiquitous membrane constituents whose metabolites function as signaling molecules in eukaryotic cells. Sphingosine 1-phosphate, a key sphingolipid second ...
Sphingosine-phosphate lyase enhances stress-induce...[J Biol Chem ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical articles back to ...
Sphingosine kinase 1 (SPHK1)
Human protein-coding gene SPHK1. Represented by 203 ESTs from 107 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 139253 - Hs.68061]
US 6239297 - Sphingosine derivatives and medicinal composition
The present invention intends to provide a derivative of sphingosine analogue that is able to regulate the functions of sphigolipid, and its pharmaceutical
TNF-{{alpha}}-Induced Sphingosine 1-Phosphate Inhibits Apoptosis ...
Human hepatocytes usually are resistant to TNF-cytotoxicity. In mouse or rat hepatocytes, repression of NF-B activation is sufficient to induce TNF--mediated apoptosis.
US 5110987 - Method of preparing sphingosine derivatives
A method of preparing a substituted derivative of sphingosine comprising the steps of reducing serine methyl ester by a hydride reagent to form an aldehyde or
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Sphingosine (2-amino-4-octadecene-1,3-diol) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.

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These recent articles mention Sphingosine
Resveratrol from red wine could treat major illnesses
eMaxHealth.com
Resveratrol inhibited the formation of two important molecules that cause inflammation - sphingosine kinase and phospholipase D. The researchers say resveratrol from red wine might be useful for developing new compounds to treat life-threat...
Lipid involved with gene regulation uncovered
PhysOrg
(PhysOrg.com) -- Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that could lead to a n...
Blood-Borne Molecule Helps Regulate Blood-Vessel Integrity
Medical News Today
TITLE: Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice AUTHOR: Shaun R. Coughlin University of California, San Francisco, San Francisco, USA. View the PDF of this article at: ...
Oral Fingolimod Appears to Reduce Inflammation in Multiple Sclerosis
Medscape News
Fingolimod is a sphingosine 1-phosphate receptor modulator, and Dr. Comi pointed out at the meeting that all of the oral agents in development for multiple sclerosis are showing increased risks. Safety Concerns "It is an important problem,"...
Drug Targets Killer Cytokine Storm From Flu
Newsblaze.com
Scripts Researchers say sphingosine analog AAL-R can block the immune system response triggering a "cytokine storm." http://www.scripps.edu/news/press/012009.html The flu causes death one of two ways - either by overwhelming the system of v...
Exelixis Reports 2Q 2009 Financial Results
TradingMarkets.com
- Established an exclusive, worldwide collaboration with Boehringer Ingelheim to discover, develop and commercialize sphingosine-1-phosphate type 1 receptor (S1P1) agonists for the treatment of autoimmune diseases. Exelixis received a $15 m...
Scientists uncork a potential secret of red wine's health benefits
Science Centric
They found that resveratrol used a one-two punch to stop inflammation in the mice by preventing the body from creating two different molecules known to trigger inflammation, sphingosine kinase and phospholipase D. This finding suggests that...
Lpath, a Developer of Lipid-Targeting Drugs, Nears a Fork in the Road
Xconomy
The company’s experimental drug neutralizes a lipid called sphingosine-1-phosphate, which cancer cells use to form new blood vessels. The theory is that cancer cells will die if they cannot access the blood supply. The effect of the drug .....