What we found on the web about Paclitaxel
Paclitaxel - Wikipedia, the free encyclopedia
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E ...
Paclitaxel total synthesis - Wikipedia, the free encyclopedia
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an important drug in the ...
Paclitaxel, Taxol and Onxal - Chemotherapy Drugs, Chemo Drug Side Effects
Paclitaxel is an anti-cancer chemotherapy drug classified as a plant alkaloid, a ... The nurse or doctor who gives Paclitaxel must be carefully trained. ...
Paclitaxel
Drug details for Paclitaxel. ... Paclitaxel is an intravenous (IV) medication. ... Paclitaxel slows or stops the growth and spread of cancer cells in the body. ...
PACLITAXEL - INJECTION (Taxol) side effects, medical uses, and drug ...
Consumer information about the medication PACLITAXEL - INJECTION (Taxol), includes side effects, drug interactions, recommended dosages, and storage information. Read more about ...
AIDSinfo - HIV/AIDS Drug Information - Paclitaxel
In addition, paclitaxel induces abnormal arrays of microtubule bundles ... Peak plasma concentrations of paclitaxel following IV administration exhibit ...
paclitaxel - definition of paclitaxel by the Free Online Dictionary ...
pac·li·tax·el (p k l-t k s l) n. An anticancer drug derived from the bark of the Pacific yew tree and used in the treatment of ovarian and breast cancer that has not responded ...
Paclitaxel - Yahoo! Health
Before you receive paclitaxel, tell your doctor if you have liver disease, heart disease, or a severely ... information I should know about paclitaxel? ...
Cyberbotanica: Paclitaxel (Taxol) & Docetaxel (Taxotere)
P aclitaxel and docetaxel are taxoid drugs extracted from the bark of the Pacific yew and the needles of the English yew, respectively. Both work against cancer by interfering with ...
paclitaxel - definition of paclitaxel in the Medical dictionary - by ...
paclitaxel /pac·li·tax·el/ (pak″lĭ-tak´sel) an antineoplastic that promotes and stabilizes polymerization of microtubules, isolated from the Pacific yew tree (Taxus ...
Pharmacokinetics of Paclitaxel-Containing Liposomes in Rats
The goal of this study was to determine the formulation dependence of paclitaxel ... Paclitaxel was administered intravenously in either multilamellar (MLV) ...
taxol
(paclitaxel) should be administered under the supervision of a physician ... Paclitaxel is a novel antimicrotubule agent that promotes the assembly of microtubules ...
paclitaxel - offers from Buyers, importers, purchasers, resellers ...
paclitaxel buyers directory - over 3,000,000 registered importers and exporters. paclitaxel importers, paclitaxel buyers, paclitaxel purchasers, resellers, traders and paclitaxel ...
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{{drugbox | | IUPAC_name = (2α,​4α,​5β,​7β,​10β,​13α)-​4,​10-​bis(acetyloxy)-​13-​{1​oxy}-​1,​7-​dihydroxy-​9-​oxo-​5,​20-​epoxytax-​11-​en-​2-​yl benzoate | image = Taxol.svg | width = 350 | image2 = Taxol(Paclitaxel)3D.png | CAS_number = 33069-62-4 | ChemSpiderID = 10368587 | ATC_prefix = L01 | ATC_suffix = CD01 | ATC_supplemental =
ATC: CD03 (paclitaxel poliglumex) | PubChem = 36314 | DrugBank = APRD00259 | C=47 | H=51 | N=1 | O=14 | molecular_weight = 853.906 g/mol | bioavailability = 6.5% (oral) | protein_bound = 89 to 98% | metabolism = Hepatic (CYP2C8 and CYP3A4) | elimination_half-life = 5.8 hours | excretion = Fecal and urinary | pregnancy_AU = | pregnancy_US = D | pregnancy_category = | legal_status = Rx-=only | routes_of_administration = iv }} Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.

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These recent articles mention Paclitaxel
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