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Osteopontin - Wikipedia, the free encyclopedia
Secreted phosphoprotein 1 (SPP1), also known as bone sialoprotein I (BSP-1), early T-lymphocyte activation (ETA-1), and most commonly as osteopontin (OPN), is a human gene product ...
Georg F. Weber - Wikipedia, the free encyclopedia
Osteopontin and variant CD44 interact, and this is essential for metastasis by several types of cancer. 2. Multiple osteopontin splice variants are present in malignant, but not in ...
Increased Expression of Osteopontin Contributes to the Progression of ...
Increased Expression of Osteopontin Contributes to the Progression of Prostate Cancer Ani C. Khodavirdi 1, Zhigang Song 1, Shangxin Yang 2, Chen Zhong 1, Shunyou Wang 3, Hong Wu 3 ...
HUMANIZED ANTI-HUMAN OSTEOPONTIN ANTIBODY - Patent application
Abstract: The present invention provides a humanized anti-human osteopontin antibody having better activities (antigen binding activity, leukocyte migration inhibitory ...
Osteopontin-ELISA
Welcome to Osteopontin-ELISA.com. IBL-America, in conjunction with our partner, IBL-Japan, offers Osteopontin ELISA kits for human, mouse and rat samples.
Osteopontin Expression and Serum Levels in Metastatic Uveal Melanoma ...
(Investigative Ophthalmology and Visual Science. 2006;47:802-806.) © 2006 by The Association for Research in Vision and Ophthalmology, Inc. doi:10.1167/iovs.05-0422
osteopontin
Properties, distribution, function: Osteopontin (OP) is a non-collagenous, acidic, sialic acid-rich phosphorylated glycoprotein with a molecular weigh of 44 kDa; it binds to ...
Osteopontin, a New Prognostic Biomarker in Patients With Chronic Heart ...
Osteopontin, a New Prognostic Biomarker in Patients With Chronic Heart Failure Mark Rosenberg, MD; Christian Zugck, MD; Manfred Nelles, MD; Claus Juenger, MD, MPH; Derk Frank ...
Osteopontin and colon cancer progression. [Clin Exp Metastasis. 2003 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical articles back to ...
Osteopontin and its Integrin Receptor {alpha}vß3 Are Upregulated ...
Osteopontin and its Integrin Receptor v ß 3 Are Upregulated During Formation of the Glial Scar After Focal Stroke Julie A. Ellison, PhD; James J. Velier, PhD; Patricia Spera, PhD ...
Osteopontin (Cytokines & Cells Encyclopedia - COPE)
Cytokines & Cells Online Pathfinder Encyclopaedia ... Osteopontin. abbr. OPN or OP or Osp. ALTERNATIVE NAMES. The name osteopontin was proposed for the bone-specific sialoprotein ...
Osteopontin Is Expressed in Human Aortic Valvular Lesions -- O'Brien ...
Osteopontin Is Expressed in Human Aortic Valvular Lesions Presented in part at the 66th Scientific Sessions of the American Heart Association, Atlanta, Ga, November 8-11, 1993.
osteopontin - Medical Definition
A phosphorylated glycoprotein that is abundant in bone mineral matrix and accelerates bone regeneration and remodeling. It is also produced in other tissues and plays a role in the ...
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PBB: geneid=6696 Secreted phosphoprotein 1 (SPP1), also known as bone sialoprotein I (BSP-1), early T-lymphocyte activation (ETA-1), and most commonly as osteopontin (OPN), is a human gene product, which is also conserved in other species. Osteopontin is a glycoprotein that was first identified in 1986 in osteoblasts. The prefix of the word "osteo" indicates that the protein is expressed in bone, although it is also expressed in other tissues. The suffix "-pontin" is derived from "pons," the Latin word for bridge, and signifies osteopontin's role as a linking protein. Osteopontin is an extracellular structural protein and therefore an organic component of bone. Synonyms for this protein include sialoprotein I and 44K BPP (bone phosphoprotein).

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These recent articles mention Osteopontin
OvaSure: new ovarian cancer test
Savannah Morning News
Thanks hbonny for your question. OvaSure is a blood test developed by Yale University for the detection of ovarian cancer. The test consist of six markers: leptin, prolactin, osteopontin, insulin-like growth factor II, macrophage inhibitory...
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Science Centric
Nicotine promotes the expression osteopontin, and high levels of osteopontin have been reported in pancreatic ductal carcinoma (PDA). Dr Arafat and her research team analysed PDA samples and confirmed that the isoform, called OPNc, was also...
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... several years' work carried out at the University to investigate the genes that cause cancerous tumors to travel to other tissues in the body. To date, three other metastasis-inducing genes have been discovered – S100A4, osteopontin ...
Nicotine may advance pancreatic cancer
United Press International
The OPNc expression also correlated with higher expression levels of osteopontin. Premalignant lesions expressed no OPNc. "This is the first time a relationship between nicotine and OPNc expression has been identified," study leader Dr. Hwy...
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Prior animal work in co-founder Dr. Cecilia Giachelli’s laboratory at the University of Washington demonstrated osteopontin’s ability to prevent further calcification and to remove existing calcification from the vasculature ...
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In a development that could lead to a novel approach to the treatment of a devastating lung disease, biochemists at The University of Texas Health Science Centre at Houston report they are the first to link the osteopontin (OPN) protein to ...
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