Nitrile butadiene rubber (NBR) is a family of unsaturated copolymers of 2-propenenitrile and various butadiene monomers (1,2-butadiene and 1,3-butadiene). Although its physical and chemical properties vary depending on the polymer's composition of nitrile (the more nitrile within the polymer, the higher the resistance to oils but the lower the flexibility of the material), this form of synthetic rubber is generally resistant to oil, fuel, and other chemicals. Its resilience makes NBR a useful material for disposable lab, cleaning, and examination gloves. It is used in the automotive industry to make fuel and oil handling hoses, seals, and grommets. NBR's ability to withstand a range of temperatures from −40 °C to +120 °C makes it an ideal material for extreme automotive applications. Nitrile butadiene is also used to create moulded goods, footwear, adhesives, sealants, sponge, expanded foams, and floor mats. Nitrile rubber is more resistant than natural rubber to oils and acids, but has inferior strength and flexibility. Nitrile gloves are nonetheless three times more puncture-resistant than rubber gloves. Nitrile rubber is generally resistant to aliphatic hydrocarbons. Nitrile, like natural rubber, can be attacked by ozone, aromatic hydrocarbons, ketones, esters and aldehydes.

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