What we found on the web about Nanopore
NANOPORE HOME. MISSION. PROJECTS. Nanopore Sequencing. Solid State Nanopores. Ion Beam Sculpting ... Group Internal WIKI © 2001 Harvard University. All rights ...
DNA - nanopore interaction reduces the ionic current (Biophysical Journal, 87:2086-2097, 2004) ... A single nanopore separates two compartments filled with ...
PhysOrg.com: Researchers at Purdue's Birck Nanotechnology Center have shown how 'nanopore channels' can be used to rapidly and precisely detect specific sequences of ...
Click here to view an animation of BASE TM nanopore sequencing Nanopores. ... Oxford Nanopore announces Advisory Board, UCSC agreement 19 August 2008Read more...
A U.K. company hopes to dramatically reduce the cost of reading a person's genome. ... The nanopore system is built into an array on a silicon chip. ...
A team led by physicists at the University of California, San Diego has shown the feasibility of a fast, inexpensive technique to sequence DNA as it passes through tiny pores.
Nanopore Sequencing Our development of solid state nanopores and our studies of DNA translocation through these nanopores suggest how a nanopore could be the core of an ...
Nanopore-based detection can report directly, or indirectly, on single molecule kinetics. The nanopore-based detector can directly measure molecular ...
Applied voltage draws a DNA strand and surrounding ionic solution through a pore of nanometer dimensions. The various DNA units in the strand block ion flow by differing amounts.
A nanopore array with diameter of 30 nm was fabricated by use of focused ion beam (FIB) ... open single nanopore with a ion detection system under the ...
Oxford Nanopore Technologies single licensing deal with Harvard specifically covers research discoveries made in the labs of three investigators at Harvard and ...
A team led by physicists at the University of California, San Diego has shown the feasibility of a fast, inexpensive technique to sequence DNA as it passes through ...
Clive G. Brown joins Oxford Nanopore from the Wellcome Trust Sanger Institute ... The nanopore molecular detection system is powerful and versatile beyond its DNA ...
To make measurements with a nanopore, polymers and electrolytes in solution are ... This page includes material from the Wikipedia article "Nanopore" ...
Nanopore sequencing is a method currently under development for determining the order in which nucleotides occur on a strand of DNA. A nanopore is simply a small hole, of the order ...
Here is what users have to say about Nanopore

__NOTOC__ A nanopore is a small pore in an electrically insulating membrane, that can be used as a single-molecule detector. A nanopore is a Coulter counter for much smaller particles. It can be a biological protein channel in a lipid bilayer or a pore in a solid-state membrane. The detection principle is based on monitoring the ionic current of an electrolyte solution passing through the nanopore as a voltage is applied across the membrane. When the nanopore is of molecular dimensions, passage of molecules (e.g., DNA) cause interruptions of the "open" current level, leading to a "translocation event" pulse. The passage of RNA or single-stranded DNA molecules through the membrane-embedded alpha-hemolysin channel (1.5 nm diameter), for example, causes a ~90% blockage of the current (measured at 1 M KCl solution) . The observation that a passing strand of RNA containing different bases results in different blocking levels has led to the nanopore sequencing hypothesis. Such sequencing, if successful, could revolutionize the field of genomics, as sequencing could be carried out in a matter of seconds. Apart from rapid DNA sequencing, other applications include separation of single stranded and double stranded DNA in solution, and the determination of length of polymers. At this stage, nanopores are making contributions to the understanding of polymer biophysics, as well as to single-molecule analysis of DNA-protein interactions.

Welcome to CWAnswers

CWAnswers is your guide to the sprawling world wide web. The directory aims to provide a useful guide made by users. You can share your knowledge as well - simply register and edit your first entry. For questions just contact the team at support - at - cwanswers.com.

Weblinks

Top 10

Things you find nowhere else.

Comments

You must be logged in to post a comment.

No comments yet on this topic. Be the first one!