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Mycobacterium is a genus of Actinobacteria, given its own family, the Mycobacteriaceae. The genus includes pathogens known to cause serious diseases in mammals, including tuberculosis and [[leprosy. The Latin prefix "myco—" means both fungus and wax; its use here relates to the "waxy" compounds in the cell wall.

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Wikipedia About Mycobacterium

Mycobacterium is a genus of Actinobacteria, given its own family, the Mycobacteriaceae. The genus includes pathogens known to cause serious diseases in mammals, including tuberculosis and [[leprosy. The Latin prefix "myco—" means both fungus and wax; its use here relates to the "waxy" compounds in the cell wall.

Microbiologic characteristics

Mycobacterial%20cell%20wall%20diagram.png

Mycobacteria are aerobic and nonmotile bacteria (except for the species Mycobacterium marinum which has been shown to be motile within macrophages) that are characteristically acid-alcohol fast. Mycobacteria do not contain endospores or capsules, and are usually considered Gram-positive. While mycobacteria do not seem to fit the Gram-positive category from an empirical standpoint (i.e. they do not retain the crystal violet stain), they are classified as an acid-fast Gram-positive bacterium due to their lack of an outer cell membrane. All Mycobacterium species share a characteristic cell wall, thicker than in many other bacteria, which is hydrophobic, waxy, and rich in mycolic acids/mycolates. The cell wall makes a substantial contribution to the hardiness of this genus.

Many Mycobacterium species adapt readily to growth on very simple substrates, using ammonia or amino acids as nitrogen sources and glycerol as a carbon source in the presence of mineral salts. Optimum growth temperatures vary widely according to the species and range from 25 °C to over 50 °C.

Some species can be very difficult to culture (i.e. they are fastidious), sometimes taking over two years to develop in culture.Fact: date=August 2007 Further, some species also have extremely long reproductive cycles — M. leprae, may take more than 20 days to proceed through one division cycle (for comparison, some E. coli strains take only 20 minutes), making laboratory culture a slow process. In addition, the availability of genetic manipulation techniques still lags far behind that of other bacterial species.

A natural division occurs between slowly– and rapidly–growing species. Mycobacteria that form colonies clearly visible to the naked eye within 7 days on subculture are termed rapid growers, while those requiring longer periods are termed slow growers. Mycobacteria are slightly curved or straight rods between 0.2-0.6 µm wide by 1.0-10 µm long.

Pigmentation

Some mycobacteria produce carotenoid pigments without light. Others require photoactivation for pigment production.

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Mycobacterium ulcerans - Wikipedia, the free encyclopedia

Epidemiology of Mycobacterium ulcerans infection (Buruli ulcer) at Kinyara, Uganda" ... Human Mycobacterium ulcerans infections developing at sites of trauma to skin" ...en.wikipedia.org/wiki/Mycobacterium_ulcerans

ParaTB pages:- Does Mycobacterium paratuberculosis cause Crohn's disease?

See Mycobacterium paratuberculosis Cervical Lymphadenitis followed five years ... See the page "Mycobacterium Paratuberculosis in Animals" for more information. ...alan.kennedy.name/crohns/welcome.htm

eMedicine - Mycobacterium Avium-Intracellulare : Article by Janak Koirala

Mycobacterium avium complex (MAC) consists of two species—M avium and ... Mycobacterium Kansasii. Pneumonia, Aspiration. Pneumonia, Bacterial. Pneumonia, Fungal ...www.emedicine.com/med/topic1532.htm

eMedicine - Mycobacterium Chelonae : Article by F Matthew Kuhlmann

Mycobacterium chelonae and Mycobacterium abscessus are nontuberculous ... In contrast with Mycobacterium fortuitum infection, the skin lesions caused by M ...www.emedicine.com/MED/topic1533.htm

Mycobacterium avium subspecies paratuberculosis - MicrobeWiki

A Microbial Biorealm page on the genus Mycobacterium avium subspecies paratuberculosis ... Mycobacterium avium subspecies paratuberculosis (Map) is the ...microbewiki.kenyon.edu/index.php/Mycobacterium_avium_subspec...

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JCI online early table of contents: Oct. 1, 2008

EurekAlert!( Journal of Clinical Investigation ) This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Oct. 1, 2008, in the JCI, including: Loss of the protein target of lithium disrupts normal mouse embryonic heart development; Restoring PTEN protein function in leukemic cells; Pinpointing a crucial role in the heart for one HDAC ....http://www.eurekalert.org/pub_releases/2008-10/joci-joe09290...

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NDTVTo read the biggest stories of the day on your mobile, type mobile.ndtv.com on your phone browser. Are authorities to be blamed for temple stampede?http://www.ndtv.com/convergence/ndtv/story.aspx?id=NEWEN2008...

TB Bacterium Uses Its Sugar Coat to Sweeten Its Chances of Living in Lungs

NewswiseCommon strains of tuberculosis-causing bacteria have hijacked the human body's immune response to play tricks on cells in the lungs, scientists say. The secret weapon in this stealth attack is sugar.http://www.newswise.com/articles/view/544791/?sc=rsmn

TB Bacterium Uses Its Sugar Coat To Sweeten Its Chances Of Living In Lungs

Medical News TodayCommon strains of tuberculosis-causing bacteria have hijacked the human body's immune response to play tricks on cells in the lungs, scientists say. The results of this takeover are mixed. The cells essentially welcome the bacteria into the lungs and invite them to stay a while, meaning the human host becomes infected with the TB bacterium.http://www.medicalnewstoday.com/articles/123566.php

PolyMedix Presents Data On Anti-Tuberculosis Activity Of Its Novel Antibiotic Compounds

Medical News TodayPolyMedix, Inc. an emerging biotechnology company developing acute care products for infectious diseases and acute cardiovascular disorders based on biomimetics, presented new data at the "New Directions in AIDS Treatment Research Policy and Care Symposium" in New York on September 26th, 2008.http://www.medicalnewstoday.com/articles/123491.php

News about Mycobacterium

Deciphering the genetic basis for polyketide variation among ...

BioMed Central ... are immunosuppressive and cytotoxic polyketides, comprising five naturally occurring structural variants (named A/B, C, D, E and F), produced by different species of very closely related mycobacteria including the human pathogen, Mycobacterium ... http://www.biomedcentral.com/1471-2164/9/462/abstract

Gene Identified that May Confer Susceptibility to Pulmonary ...

Genetic Engineering NewsScientists have discovered that the toll-like receptor 8 (TLR8) gene may increase susceptibility to pulmonary tuberculosis (TB). They also found that males are more vulnerable than females to Mycobacterium tuberculosis infections. TLR8 was previously ... http://www.genengnews.com/news/bnitem.aspx?name=43309496

Gene Causing Pulmonary Tuberculosis Revealed

SoftpediaTough one third of the world's population is infected with Mycobacterium tuberculosis, the bacterium that causes pulmonary tuberculosis (TB), only 5 to 10 percent of them will ever develop the disease in its active state. Why this happens remains a ... http://news.softpedia.com/news/Gene-Causing-Pulmonary-Tuberc...

Groundbreaking, lifesaving TB vaccine a step closer

PhysOrgThe Aeras Global TB Vaccine Foundation, which was founded to develop new, cost-effective TB vaccines for use in the developing world, has licensed a discovery of a protein that is able to 'wake up' dormant Mycobacterium tuberculosis bacteria that ... http://www.physorg.com/news142654588.html

New vaccines may not reduce TB incidence

PhysOrgTuberculosis is caused by infection with the bacterium Mycobacterium tuberculosis. There are nearly nine million new cases of TB each year and two million deaths world wide. A major priority in medical research is the development of new, more ... http://www.physorg.com/news142607908.html

Search results for Mycobacterium

Mycobacterium

GENERAL CONCEPTS: Mycobacteria belong in the family Mycobacteriaceae and are part of the CMN group (Corynebacteria, Mycobacteria and Nocardia). The family Mycobacteriaceae are Gram ... http://www.cehs.siu.edu/fix/medmicro/mycob.htm

mycobacterium - definition of mycobacterium by the Free Online ...

my·co·bac·te·ri·um   (m k-b k-tîr-m) n. pl. my·co·bac·te·ri·a (-tîr-) Any of various slender, rod-shaped, aerobic bacteria of the genus Mycobacterium, which includes ... http://www.thefreedictionary.com/mycobacterium

mycobacterium definition of mycobacterium in the Free Online ...

mycobacterium. Any of the rod-shaped bacteria that make up the genus Mycobacterium. The two most important species cause tuberculosis and leprosy in humans; another species causes ... http://encyclopedia2.thefreedictionary.com/mycobacterium

Mycobacterium tuberculosis

The Microbiology Video Library. ... Mycobacterium tuberculosis "Captain among these Men of Death" (John Bunyon 1660)http://www.microbiologybytes.com/video/Mtuberculosis.html

eMedicine - Mycobacterium Chelonae : Article by F Matthew Kuhlmann

Mycobacterium chelonae and Mycobacterium abscessus are nontuberculous mycobacteria (NTM), a grouping that encompasses alhttp://www.emedicine.com/med/topic1533.htm
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Empowered Health News | Crohn's Disease and Cow's Milkhttp://www.empowereddoctor.com/story_1364.html Crohn's disease is a condition associated with chronic intestinal inflammation that causes pain, bleeding, and diarrhea, affecting...Flash - Video

Answers for Mycobacterium

jmerriman3where is mycobacterium sp found or where does it live? does it cause disease?why is it important in society?jmerriman3mycobacterium causes tuberculosis and Hansen's disease (Leprosy). Humans are its natural resevior, so they can be found in people, different species of mycobacterium have been found in cows too, which...annieMy ESR is130 and mycobacterium combo Igm test is positive, what does it mean?annieYour results indicate that you have active Mycobacterium infection. I hope you are being treated appropriately by a good doc! The high ESR indicates an acute inflammatory response. IgM are your s...janine260What are the broth and slant properties of mycobacterium tuberculosis?janine260Broth and slant properties? I hope this is what you are looking for... Mycobacteria tuberculosis (M. tb) grows well on Lowenstein-Jensen media (LJ media), which is an egg based media that contain...College StudentWhat specific genes in Mycobacterium tuberculosis are responsible for it's mutation resistance?College Studentthere are certain plasmids bacteria has that enables it to resist, and evolve, and do all sorts of stuff scientists look at and say whoa, whoa , did you see that?! that's cool right! yo man dat stuff ...michelle rHow might acid fast characteristic of Mycobacterium enhance to cause diease?michelle rIt wouldn't be damaged by the acid in the stomach, and could still be viable upon reaching the intestines.
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