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PBB: geneid=4057 Lactoferrin (LF), also known as lactotransferrin (LTF), is a globular multifunctional protein with antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. Lactoferrin is found in milk and many mucosal secretions such as tears and saliva. Lactoferrin is also present in secondary granules of PMN and also is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk.

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Blogs for Lactoferrin

Lactoferrin Blog Entries // Blog Post Tag Search // BlogCatalog

Blog Tags. Post Tags. 2 items found. Tag Search Results For 'lactoferrin' (2) ... Lactoferrin for Cats with FIV ... Mobile BlogCatalog Blog TOS BlogCatalog ...www.blogcatalog.com/post-tag/lactoferrin/

Lactoferrin, Lactoferrin research, colostrum lactoferrin

Learn about lactoferrin and colostrum lactoferrin at colostrum.lifetips.com. ... we're looking to recruit a Guru to blog, write a 101 tip Colostrum book, and ...colostrum.lifetips.com/cat/60863/lactoferrin/index.html

The Biotech Weblog: Lactoferrin And Lysozymes Production From Rice

Lactoferrin and lysozymes are two proteins naturally ... Half of me- The blog behind success. The cinnamon and honey trick. Coffee, good or bad for you? ...www.biotech-weblog.com/50226711/lactoferrin_and_lysozymes_pr...

The Motherwear Breastfeeding Blog: Iron supplements for breastfed ...

About a year ago I started getting lots of questions from moms at the ... Lactoferrin has the job of binding with iron in the baby's gut and getting it ...breastfeeding.blog.motherwear.com/2007/03/iron_supplement.ht...

The Biotech Weblog: Lactoferrin Aids in Treatment of H. Pylori Infections

... adding a bovine protein called lactoferrin to the existing approaches used to ... Biotech Blog. Biotech Investing. Biotech Licensing. CATO Biotech Directory ...www.biotech-weblog.com/50226711/lactoferrin_aids_in_treatmen...

Wikipedia About Lactoferrin

PBB: geneid=4057 Lactoferrin (LF), also known as lactotransferrin (LTF), is a globular multifunctional protein with antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. Lactoferrin is found in milk and many mucosal secretions such as tears and saliva. Lactoferrin is also present in secondary granules of PMN and also is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk.

Structure

Lactoferrin belongs to the transferrin family proteins (TF, melanotransferrin, ovotransferin, etc.). Its molecular mass is 80,000 u (80 kDa). It generally contains two bound Fe+2 ions. It contains 4 identical domains, with two surrounding each iron atom.

Function

Lactoferrin antimicrobial activity is due partly to its high affinity for Fe3+ (ferric state). LF proteolysis produces lactoferricin, kaliocin-1 small peptides with antimicrobial activity. The combination of iron and lactoferrin in mucosal secretions modulate the ability and aggregation of pathogenic bacteria, and inhibit both bacteria and viruses by binding to host cells/viral particles. This inhibits the ability of bacteria and viruses to attach to cell membranes. It is also an antifungal agent.

Lactoferrin receptors have been found on brush-border cells, PMN, monocytes, Mφ and activated lymphocytes.

Lactoferrin inhibits dendritic cell-mediated HIV-1 transmission by blocking gp120 to DC-SIGN , which is a critical protein that never changes regardless of strain.

Genetics

In humans, the lactoferrin gene (LTF) is located on chromosome 3; location: 3q21-q23.

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News about Lactoferrin

EyeScience's New Ocular Nutrition Supplements Available at CVS Stores

PR NewswireEyeScience Dry Eye Formula(TM) contains a proprietary blend of an omega-3 essential fatty acid; flaxseed oil; lactoferrin; magnesium; and Vitamins B-6, C and E. This advanced formulation, in an easy-to-swallow soft gel capsule, improves absorption ... http://sev.prnewswire.com/health-care-hospitals/20081217/CLW...

Aslan Group Pays $25M for Rights to Pharming’s Lactoferrin

Genetic Engineering NewsPharming and Aslan, based in Istanbul, signed a licensing agreement to further develop, manufacture, and market Pharmings’ human lactoferrin product (hLF). This agreement was made on the heels of an earlier one this year, when the companies ... http://www.genengnews.com/news/bnitem.aspx?name=45796876

South Korea finds melamine in New Zealand product

ReutersThe Korea Food and Drug Administration said in a statement that the product, lactoferrin, was produced by Tatua Cooperative Diary Company of New Zealand. South Korea was banning all other products made by the company pending further tests, it said. No ... http://www.reuters.com/article/healthNews/idUSTRE4910UK20081...

Lipton Milk Tea Powder Recalled In Asia

CBS NewsIn New Zealand, the Tatua Cooperative Dairy Co. on Monday stopped exports of the dairy protein lactoferrin, used mainly in baby formula, after tests showed it contained traces of melamine. Tatua said a Chinese customer told its agent two weeks ago ... http://www.cbsnews.com/stories/2008/09/30/world/main4489172....

Why is snot green?

Guardian UnlimitedOne of these is lactoferrin and other enzymes are dependent on iron for their activity. The colouration therefore comes from the iron. Ferrous iron compounds are green. It turns yellow the bacteria have been around for a while and other cells start ... http://www.guardian.co.uk/notesandqueries/query/0,,-8250,00....

Search results for Lactoferrin

LACTOFERRIN CAPS (250mg)

Read More . . . This is for those who do not want to consume large amounts of whey powder. Scientific literature shows that Lactoferrin: Scavenges excess iron to protect against ... http://www.lifeextensionvitamins.com/laccap.html

Lactoferrin – A Novel Bone Growth Factor

Dorit Naot, PhD, Andrew Grey, MD, Ian R Reid, MD, and Jillian Cornish, PhDhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...

Antiinflammatory Activities of Lactoferrin -- Conneely 20 (Supplement ...

Journal of the American College of Nutrition, Vol. 20, No. 90005, 389S-395S (2001) Published by the American College of Nutrition Antiinflammatory Activities of Lactoferrinhttp://www.jacn.org/cgi/content/full/20/suppl_5/389S

LACTOFERRIN

LACTOFERRIN. Lactoferrin is secreted in milk, tears and bile. It is elevated by inflammation and some cancers. It has been suggested to have a number of functional properties ... http://www.fst.ohio-state.edu/People/HARPER/Functional-foods...

LE Magazine, October 2000 - Report: Lactoferrin: The Bioactive ...

LE Magazine, October 2000 - Report: Lactoferrin: The Bioactive Peptide that Fights Diseasehttp://www.lef.org/magazine/mag2000/oct2000_report_lactoferr...

Wikipedia results for Lactoferrin

Lactoferrin - Wikipedia, the free encyclopedia

Lactoferrin (LF), also known as lactotransferrin (LTF), is a globular multifunctional protein with antimicrobial activity (bacteriocide, fungicide) and is part of the innate ... http://en.wikipedia.org/wiki/Lactoferrin

Ventria Bioscience - Wikipedia, the free encyclopedia

Ventria's product pipeline is based on recombinant lactoferrin and lysozyme for use in medical foods, bioprocessing, cell culture and as a topical anti-infective.http://en.wikipedia.org/wiki/Ventria_Bioscience

Tears - Wikipedia, the free encyclopedia

Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium. Some of the substances in lacrimal ... http://en.wikipedia.org/wiki/Tears

Herman the Bull - Wikipedia, the free encyclopedia

All calves inherited the lactoferrin production gene. [4] Herman went on to father 55 calves [3]. Dutch law demanded that he be slaughtered at the conclusion of his role in the ... http://en.wikipedia.org/wiki/Herman_the_Bull

Globulin - Wikipedia, the free encyclopedia

Globulin is one of the two types of serum proteins, the other being albumin. ... Beta-lactoglobulin (Lactoferrin) · Thyroglobulin · Alpha-lactalbuminhttp://en.wikipedia.org/wiki/Globulin
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