Heparanase - Wikipedia, the free encyclopedia
Heparanase, also known as HPSE, is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter ...
HPSE2 - Wikipedia, the free encyclopedia
Heparanase-2 is an enzyme that in humans is encoded by the HPSE2 gene. [1] [2] ... McKenzie E, Tyson K, Stamps A, Smith P, Turner P, Barry R, Hircock M, Patel S, Barry E ...
Translocation of Active Heparanase to Cell Surface Regulates ...
After Ag capture and exposure to danger stimuli, maturing dendritic cells (DCs) migrate to regional lymph nodes, where antigenic peptides are presented to T lymphocytes.
Anti-heparanase monoclonal antibody enhances heparanase enzymatic ...
Anti-heparanase monoclonal antibody enhances heparanase enzymatic activity and facilitates wound healing Svetlana Gingis-Velitski *, Rivka Ishai-Michaeli, Israel Vlodavsky *,1 and ...
InSight Biopharmaceuticals - Heparanase
Heparanase : InSight's scientists were the first to clone the gene coding for Heparanase, a unique human enzyme playing a key role in cancer and inflammation.
Heparanase: Screening Tool for Tongue Cancer
: Heparanase levels were significantly elevated in tongue cancer patients, suggesting that it might be useful as a diagnostic tool to monitor progression of this disease and ...
Heparanase Inhibitor Shows Potential as Cancer Drug
Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body’s own polysaccharide heparan sulfate into shorter ...
Heparanase Induces Vascular Endothelial Growth Factor Expression ...
Heparanase Induces Vascular Endothelial Growth Factor Expression: Correlation with p38 Phosphorylation Levels and Src Activation Anna Zetser 1, Yulia Bashenko 1, Evgeny Edovitsky 2 ...
Journal of Clinical Investigation -- Molecular properties and ...
Perspective Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. Israel Vlodavsky and Yael Friedmann. Department of Oncology, Hadassah-Hebrew ...
Products: Heparanase Assay
Heparanase is an enzyme that cleaves heparan sulfate thereby releasing growth factors that are implicated in tumor cell proliferation, metastasis and angiogenesis.
Heparanase (HPSE)
Human protein-coding gene HPSE. Represented by 103 ESTs from 59 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 137179 - Hs.44227]
Heparanase Affects Adhesive and Tumorigenic Potential of Human Glioma ...
Heparanase Affects Adhesive and Tumorigenic Potential of Human Glioma Cells Anna Zetser 1, Yulia Bashenko 1, Hua-Quan Miao 2, Israel Vlodavsky 1 and Neta Ilan 1
Development of a homogeneous heparanase assay using HTRF® technology
www.htrf-assays.com Development of a homogeneous heparanase assay using HTRF ® technology Chikashi Tokuda 1, Laurence Jacquemart 2 and Marc Préaudat 2 1 Nihon Schering k.k ...
Mammalian heparanase: Gene cloning, expression and function in tumor ...
Article: Nature Medicine 5, 793 - 802 (1999) doi:10.1038/10518 Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
