What we found on the web about Gankyrin
Gankyrin is a recently discovered oncoprotein that is a component of the 19S regulatory cap of the proteasome. Structurally, it contains a 33-amino acid ankyrin repeat that forms a ...
"Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome.". J. Biol. Chem. 277 (13): 10893–902.
Protein: 26S proteasome non-ATPase regulatory subunit 10, gankyrin from Human (Homo sapiens) [TaxId: 9606] SQ O75832 Lineage: Root: scop; Class: Alpha and beta proteins (a+b) [53931]
Extra Views The Oncoprotein Gankyrin Negatively Regulates Both p53 and RB by Enhancing Proteasomal Degradation Hiroaki Higashitsuji, Yu Liu, R. John Mayer and Jun Fujita
Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26 Molecular Cell, Volume 32, Issue 2, 24 October 2008, Pages 180-189 Yaara Ofir ...
"Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome.". J. Biol. Chem. 277 (13): 10893–902.
Furthermore, a gankyrin/CDK4 structural model will be generated using both NMR and mutagenesis data, hi collaboration with C. Weghorst, we will characterize gankyrin mutants ...
PDB id: 2dwz: Name: Oncoprotein: Title: Structure of the oncoprotein gankyrin in complex with s6 atpase of the 26s proteasome Structure: 26s proteasome non-atpase regulatory ...
Here, we report the structure of gankyrin in complex with the C-terminal domain of S6 ATPase. Almost all of the seven ankyrin repeats of gankyrin interact, through its concave ...
This is a project designed to characterize Gankyrin, a protein overexpressed in certain types of cancer cells. Gankyrin is a protein which is overexpressed in certain types of ...
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