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Esomeprazole - Wikipedia, the free encyclopedia
Esomeprazole (pronounced /iːsɵˈmɛprəzoʊl/) is a proton pump inhibitor (brand names Sompraz, Zoleri, Nexium®, Lucen, Esopral; Axagon in Italy, Nexiam in Belgium) developed ...
Omeprazole - Wikipedia, the free encyclopedia
Esomeprazole is the S-enantiomer in the pure form. According to AstraZeneca, omeprazole undergoes a chiral shift in vivo which converts the inactive R-enantiomer to the active S ...
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Esomeprazole ( ) is a proton pump inhibitor (brand names Sompraz, Zoleri, Nexium®, Lucen, Esopral; Axagon in Italy, Nexiam in Belgium) developed and marketed by AstraZeneca which is used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome. Esomeprazole is the S-enantiomer of omeprazole (marketed as Losec/Prilosec), and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic mixture of omeprazole. However, this greater efficacy has been disputed, with someWho: date=September 2009 claiming it offers no benefit from its older form.

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These recent articles mention Esomeprazole
Pozen says it will ask for pain drug approval
CNBC
The drug combines the pain reliever naproxen with esomeprazole magnesium, which is the active ingredient in AstraZeneca's heartburn drug Nexium. PN 400 is intended to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis in ...
Update From the Medical Journals: July 2009
InteliHealth
Proton pump inhibitors include omeprazole (Prilosec, Prilosec OTC), esomeprazole (Nexium), lansoprazole (Prevacid), pantoprazole (Protonix, Pantoloc) and rabeprazole (Aciphex). Other research has suggested that rebound symptoms from milder ...
CORRECTED - CORRECTED-(Aug 31)-UPDATE 1-Pozen says FDA accepts Vimovo ...
Reuters
(Corrects second paragraph in Aug. 31 story to clarify the drug Vimovo contains an immediate release form of AstraZeneca's esomeprazole, not the enteric-coated formulation found in Nexium) * Pozen to get $10 mln payment from AstraZeneca * S...
FDA Safety Changes: Tracleer, Nexium, Nexium IV, Tygacil
Medscape News
Esomeprazole (Nexium, Nexium IV) Linked to Antiretroviral Drug Interactions On January 15, the FDA approved safety labeling revisions for esomeprazole sodium injection (Nexium IV, AstraZeneca) and esomeprazole magnesium delayed-release caps...
Medicis sues Ranbaxy over generic
Phoenix Business Journal
During the 180-day period following that date, Ranbaxy will distribute the only generic Esomeprazole magnesium product in the U.S. In November 2007, Ranbaxy reached an agreement with Astellas/Boehringer Ingelheim to resolve patent litigatio...
Heartburn Drugs May Contribute to the Problem
Forbes
For this study, 120 healthy people were randomly assigned to receive 12 weeks of a placebo or eight weeks of Nexium (esomeprazole, 40 milligrams a day), followed by four weeks of placebo. Forty-four percent of individuals receiving the PPI ...
AstraZeneca Submits Marketing Authorisation Application to European ...
Phramalive.com
VIMOVO is a fixed-dose combination of enteric coated naproxen and immediate release esomeprazole under co-development by AstraZeneca and POZEN. “Nearly 151 million people worldwide suffer from osteoarthritis. However, up to one third of ...
Rebound Acid Reflux with PPIs May Induce Dependence
ABC News
After two months of taking esomeprazole (Nexium), 44 percent of healthy volunteers who started with no symptoms developed significant heartburn, acid reflux or dyspepsia, compared with 15 percent who took a harmless placebo, the scientists ...
POZEN Submits New Drug Application For VIMOVO™ (PN 400)
Medical News Today
... NASDAQ:POZN), announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the marketing approval of VIMOVO™ (PN 400), the combination of enteric coated (EC) naproxen and immediate release ...