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Wikipedia About Double-blind

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The blind method is a part of the scientific method, used to prevent research outcomes from being influenced by either the placebo effect or the observer bias. Blinded research is an important tool in many fields of research, from medicine, to psychology and the social sciences, to forensics.

Single-blind trials

Blinding is a basic tool to prevent conscious as well as subconscious bias in research. For example, in open taste tests comparing different product brands, consumers usually choose their regular brand. However, in blind taste tests, where the brand identities are concealed, consumers may favor a different brand.

Single blind describes experiments wherein information that could introduce bias or otherwise skew the result is withheld from the participants. Unlike in a double blind experiment, the experimenter will be in full possession of the facts. A trivial example of a single-blind experiment would be the Pepsi Challenge.

In a single blind experiment, the individual subjects do not know whether they are so-called "test" subjects or members of an "experimental control" group. Single-blind experimental design is used where the experimenters either must know the full facts (for example, when comparing sham to real surgery) and so the experimenters cannot themselves be blind, or where the experimenters will not introduce further bias and so the experimenters need not be blind. However, there is a risk that subjects are influenced by interaction with the researchers — known as the experimenter's bias. Single-blind trials are especially risky in psychology and social science research, where the experimenter has an expectation of what the outcome should be, and may consciously or subconsciously influence the behavior of the subject.

Double-blind trials

Double-blind describes an especially stringent way of conducting an experiment, usually on human subjects, in an attempt to eliminate subjective bias on the part of both experimental subjects and the experimenters. In most cases, double-blind experiments are held to achieve a higher standard of scientific rigour.

In a double-blind experiment, neither the individuals nor the researchers know who belongs to the control group and the experimental group. Only after all the data have been recorded (and in some cases, analyzed) do the researchers learn which individuals are which. Performing an experiment in double-blind fashion is a way to lessen the influence of the prejudices and unintentional physical cues on the results (the placebo effect, observer bias, and experimenter's bias). Random assignment of the subject to the experimental or control group is a critical part of double-blind research design. The key that identifies the subjects and which group they belonged to is kept by a third party and not given to the researchers until the study is over.

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Double Blind Clinical Study - Body Rejuvenator Natur-Aly

A double blind 3-month (90 days) study on the Body Rejuvenator Natur-Aly™ was performed ... A Randomized Double Blind Clinical Study Designed To Determine ...doubleblindstudy.org/index.html

Double bind - Wikipedia, the free encyclopedia

For the type of experiment, see double-blind. ... A double bind is a dilemma in communication in which a person receives two or ...en.wikipedia.org/wiki/Double_bind

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Double Blind - What Science Can't See & He Loves Me - He Loves Me Not

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Online Medical Dictionary and glossary with medical definitions ... Double-blind trials are thought to produce objective results, since the ...www.medterms.com/script/main/art.asp?articlekey=38696

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News about Double-blind

Transition Therapeutics Dose First Patient In Phase 2 Clinical Study Of TT-223 In Type 2 Diabetes

Medical News TodayTransition Therapeutics Inc. ("Transition" or the "Company") (NASDAQ:TTHI, TSX:TTH) announced that the first patient has been dosed in a Phase 2 clinical study of gastrin analogue, TT-223, in patients with type 2 diabetes.http://www.medicalnewstoday.com/articles/121357.php

Addrenex Pharmaceuticals Announces Positive Phase III Clinical Results For Clonicel To Treat ADHD

Medical News TodayA drug that diminishes the body's hyper-reactivity to stress has been shown to significantly reduce symptoms of attention-deficit hyperactivity disorder (ADHD) in children, according to a phase 3 clinical trial conducted by Addrenex Pharmaceuticals.http://www.medicalnewstoday.com/articles/121363.php

Circassia completes allergy tech phase II trial

PharmaBizCircassia Ltd, a specialty biopharmaceutical company focused on controlling immune system responses, announced positive results from a phase-II clinical study of its anti-allergy technology, ToleroMune, in the field of cat allergy.http://www.pharmabiz.com/article/detnews.asp?articleid=46048

Transition Therapeutics initiates dosing in Phase II diabetes study

Pharmaceutical Business ReviewCanada-based biopharmaceutical company Transition Therapeutics has announced that the first patient has been dosed in a Phase II clinical study of gastrin analogue, TT-223, in patients with type 2 diabetes.http://www.pharmaceutical-business-review.com/article_news.a...

Jazz Pharmaceuticals completes first Phase III study of fibromyalgia drug

Pharmaceutical Business ReviewUS-based specialty pharmaceutical company Jazz Pharmaceuticals has announced that the final patient has completed participation in the first Phase III pivotal clinical trial of JZP-6 for the treatment of fibromyalgia.http://www.pharmaceutical-business-review.com/article_news.a...

News about Double-blind

Sizing up music -- how many hours can I get on an MP3 player?

Guardian UnlimitedThe only way to find out which sounds better to you is to run a double-blind test with different encodings of the same music, played in a random order. You can get better sound quality by buying better headphones (or earbuds) than the ones supplied ... http://www.guardian.co.uk/technology/askjack/2007/oct/25/siz...

Dendreon says Provenge cuts deaths in trial; stock soars

Seattle Business JournalShares in the Seattle biotech (NASDAQ: DNDN) soared more than 43 percent in early trading, rising $2.25 to $7.45. Dendreon said the results of a Phase 3, randomized, double-blind, placebo-controlled clinical trial showed Dendreon reported a 20 ... http://seattle.bizjournals.com/seattle/stories/2008/10/06/da...

Dendreon reports encouraging interim data from Phase III prostate ...

Pharmaceutical Business ReviewDendreon, a biotechnology company, has completed the planned interim analysis of the Phase III, randomized, double-blind, placebo-controlled Impact clinical trial designed to assess the safety and efficacy of the investigational active cellular ... http://www.pharmaceutical-business-review.com/article_news.a...

First Comprehensive Results From The UPLIFT Trial Revealed At The ERS ...

Medical News TodayThe UPLIFT (Understanding Potential Long-term Impacts on Function with Tiotropium) study is a randomized double-blind, parallel-group, 4-year trial. One of the largest COPD trials ever undertaken, UPLIFT was aimed at comparing treatment with ... http://www.medicalnewstoday.com/articles/124318.php

Postoperative Ketamine Can Reduce Morphine Consumption and Nausea

Medscape NewsSeven French investigators report in the journal Anesthesia and Analgesia in 2008 on a prospective, randomized, double-blind, controlled trial of 81 patients with major abdominal surgery. [1] They administered ketamine intra- and postoperatively for 48 ... http://www.medscape.com/viewarticle/581018

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double blind definition |Dictionary.com

Sponsored Links Blinds Up to 87% Off Featured on ABC's Extreme Makeover Free Shipping and Free Samples. www.SelectBlinds.comhttp://dictionary.reference.com/search?q=double+blind

Double-blind definition - Medical Dictionary definitions of popular ...

Online Medical Dictionary and glossary with medical definitions ... Definition of Double-blind. Double-blind: Term used to described a study in which both the investigator or the ... http://www.medterms.com/script/main/art.asp?articlekey=38696

control group study, double-blind, random tests

control group study. A control group study uses a control group to compare to an experimental group in a test of a causal hypothesis. The control and experimental groups must be ... http://skepdic.com/control.html

Double-Blind Submission, Author Response, Rebuttal, Reviewing

Editorial: Improving Publication Quality by Reducing Bias with Double-Blind Reviewing and Author Response. June 2008. Kathryn S McKinley, The University of Texas at Austinhttp://www.cs.utexas.edu/users/mckinley/notes/blind.html

Double-blind Study

Double-blind Study  The best and most reliable form of research is the double-blind, placebo-controlled study. The purpose of this kind of study is to eliminate the ... http://healthlibrary.epnet.com/GetContent.aspx?token=e049880...
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Answers for Double-blind

sunscourWHat exactly is a "double blind study"?sunscourIt means neither the participants nor the study conductors know whether or not you have gotten the drug or a placebo =)mnansenWhat are two purposes of a double blind study?mnansenHaving a double blind study makes it so that the experimenter and the subject can't be subjective and either be biased in their observations or act in a certain way. That way, the result of the exper...punjabi15What is a control and what is involved in a double-blind study?punjabi15A control is set of data (people, cells, plants whatever you are working with) that are left in the "natural" state and our not tested in your experiment to be used as a comparison. They are however u...Hawk OWhere can I find double-blind research that proves Homeopathy works (if there is any)?Hawk Oironwood9What is a 'double blind' taste test ?ironwood9No... not necessarily blind folded. A blind tasting is where the taster doesn't know the important facts about the sample. They'll know they're eating chicken, but not the sauce on the chicken (se...
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