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Wikipedia About Double-blind

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The blind method is a part of the scientific method, used to prevent research outcomes from being influenced by either the placebo effect or the observer bias. To blind a person involved in research (whether a researcher, subject, funder, or other person) is to prevent them from knowing certain information about the process. The terms 'blind' (adj) or 'to blind' (vt) when used in this sense are figurative extensions of the literal idea of blindfolding someone. Blinded research is an important tool in many fields of research, from medicine, to psychology and the social sciences, to forensics.

There can be varying degrees of blinding (eg, single-blind, double-blind, triple-blind), as explained more below.

The opposite of a blind trial is an open trial.

Blinding is a basic tool to prevent conscious as well as subconscious bias in research. For example, in open taste tests comparing different product brands, consumers usually choose their regular brand. However, in blind taste tests, where the brand identities are concealed, consumers may favor a different brand.

Occasionally researchers prefer to use the terms masked (adj) or to mask (vt) instead of 'blind/blinded/to blind'. This preference is operative especially in ophthalmology, where the same word, 'blind', also frequently occurs in its literal sense of blindness. In these contexts it is simply more convenient to avoid any ambiguity, or annoyance to the reader, from the same word being used in two senses in close proximity. Nevertheless, in most research contexts, there is no expectation that 'blind/blinded' will be obsessively avoided via replacement with 'mask/masked'.

Single-blind trials

Single-blind describes experiments where information that could introduce bias or otherwise skew the result is withheld from the participants, but the experimenter will be in full possession of the facts.

In a single-blind experiment, the individual subjects do not know whether they are so-called "test" subjects or members of an "experimental control" group. Single-blind experimental design is used where the experimenters either must know the full facts (for example, when comparing sham to real surgery) and so the experimenters cannot themselves be blind, or where the experimenters will not introduce further bias and so the experimenters need not be blind. However, there is a risk that subjects are influenced by interaction with the researchers — known as the experimenter's bias. Single-blind trials are especially risky in psychology and social science research, where the experimenter has an expectation of what the outcome should be, and may consciously or subconsciously influence the behavior of the subject.

Double-blind trials

Double-blind describes an especially stringent way of conducting an experiment, usually on human subjects, in an attempt to eliminate subjective bias on the part of both experimental subjects and the experimenters. In most cases, double-blind experiments are held to achieve a higher standard of scientific rigour.

Search results for Double-blind

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News about Double-blind

OSI Pharmaceuticals Provides Update On Diabetes And Obesity Clinical Programs

Medical News TodayOSI Pharmaceuticals, Inc. (NASDAQ: OSIP) provided an update on the progress of two early clinical programs from its diabetes and obesity R&D operations. Phase I clinical trial data on both PSN821 and PSN602 showed positive evidence of clinical activity, and both candidates are now progressing to the next stage of clinical development.http://www.medicalnewstoday.com/articles/149754.php

AZOR(R) Receives FDA Approval as First-Line Treatment for High Blood Pressure

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James Randi prize: Scientists put a psychic's paranormal claims to the test

Guardian UnlimitedProfessional medium Patricia Putt was last week subjected to a rigorous scientific test of her powers as the first stage of her bid to claim a $1m prize from the James Randi Educational Foundation The young female volunteer in front of me could not suppress an embarrassed giggle as she sat there wearing a ski mask, wraparound sunglasses, an oversized graduation gown and a pair of white socks, a .....http://www.guardian.co.uk/science/2009/may/12/psychic-claims...

Alkermes Initiates Two New Clinical Trials Of ALKS 33

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Osmetech Chosen as Principal Supplier for a Major Clinical Trial

Business Wire via Yahoo! FinancePASADENA, Calif.----Osmetech plc , the international molecular diagnostics company, announces that it has signed an agreement as principal supplier of Warfarin Sensitivity tests for a major new US trial sponsored by the US National Heart, Lung, and Blood Institute , part of the National Institutes of Health in the US.http://biz.yahoo.com/bw/090513/20090513005266.html?.v=1

News about Double-blind

Circassia Begins Phase II Clinical Trial With Ragweed Allergy Therapy

Phramalive.comThe double-blind, randomised trial will include 50 patients with confirmed ragweed allergies, and will compare a range of ToleroMune doses with placebo. Unlike most current immunotherapies, which require careful dose escalation over many months and ... http://www.pharmalive.com/News/Index.cfm?articleid=626367

Osmetech Chosen as Principal Supplier for a Major Clinical Trial

Genetic Engineering NewsThe study has been designed as a 1,238 patient, randomized, double-blind trial which will examine the utility of using genetic information for warfarin dosing. Specifically, the COAG Trial will test two approaches to determining ... http://www.genengnews.com/news/bnitem.aspx?name=54419963

Amarin Receives Special Protocol Assessment Agreement from the FDA for ...

MSN MoneyCentralPursuant to the SPA, the Phase 3 trial will be a multi-center, placebo-controlled, randomized, double-blind, 12-week study to evaluate the efficacy and safety of two doses of AMR101, a prescription grade Omega-3 fatty acid, in ... http://news.moneycentral.msn.com/provider/providerarticle.as...

Can coffee prevent a headache?

Times of IndiaThe group examined caffeine's effects in a double-blind study, which involved the administration of caffeine and placebo capsules. Each participant's response to the caffeine or placebo was measured using brain electrical activity via ... http://timesofindia.indiatimes.com/Health/Can-coffee-prevent...

A "Cool" Way to Reduce Pain During Intravenous Cannulation

Medscape NewsEffect of Topical Alkane Vapocoolant Spray on Pain With Intravenous Cannulation in Patients in Emergency Departments: Randomised Double Blind Placebo Controlled Trial Hijazi R, Taylor D, Richardson J BMJ . 2009;338:b215 Summary In this report, the ... http://www.medscape.com/viewarticle/702358

Search results for Double-blind

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Double-blind definition - Medical Dictionary definitions of popular ...

Online Medical Dictionary and glossary with medical definitions ... Definition of Double-blind. Double-blind: Term used to described a study in which both the investigator or the ... http://www.medterms.com/script/main/art.asp?articlekey=38696

control group study, double-blind, random tests

control group study. A control group study uses a control group to compare to an experimental group in a test of a causal hypothesis. The control and experimental groups must be ... http://skepdic.com/control.html

Double-Blind Submission, Author Response, Rebuttal, Reviewing

Editorial: Improving Publication Quality by Reducing Bias with Double-Blind Reviewing and Author Response. June 2008. Kathryn S McKinley, The University of Texas at Austinhttp://www.cs.utexas.edu/users/mckinley/notes/blind.html

Double-blind Study

Double-blind Study  The best and most reliable form of research is the double-blind, placebo-controlled study. The purpose of this kind of study is to eliminate the ... http://healthlibrary.epnet.com/GetContent.aspx?token=e049880...

Wikipedia results for Double-blind

Blind experiment - Wikipedia, the free encyclopedia

There can be varying degrees of blinding (eg, single-blind, double-blind, triple-blind), as explained more below. The opposite of a blind trial is an open trial.http://en.wikipedia.org/wiki/Double-blind

Double bind - Wikipedia, the free encyclopedia

For the type of experiment, see double-blind. ... A double bind is a dilemma in communication in which an individual (or group) receives ... http://en.wikipedia.org/wiki/Double_bind

High fidelity - Wikipedia, the free encyclopedia

Purists generally avoid referring to these systems as high fidelity, though some are capable of very good quality sound reproduction. Ascertaining high fidelity: double-blind testshttp://en.wikipedia.org/wiki/High_fidelity

Randomized controlled trial - Wikipedia, the free encyclopedia

... Types of trials. Trials may be open, blind or double-blind. Open trialhttp://en.wikipedia.org/wiki/Randomized_controlled_trial

Ploidy - Wikipedia, the free encyclopedia

Ploidy is the number of complete sets of chromosomes in a biological cell. In humans, the somatic cells that comprise the body are diploid (containing two complete sets of ... http://en.wikipedia.org/wiki/Diploid
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Answers for Double-blind

DetunedRadioHow would you apply double blind - Psychology Experiment?DetunedRadioYou assign researchers to two groups, making sure the researchers don't know what the other group is to do. You have the control group do something passive, like read books. Have the researcher mak...Dark AWhat is the placebo effect, and why are blind & double blind?Dark APlacebo effect is like the othe person says....The doctor gives you a pill that he says will stop a pain, or cheer you up or something. But it's just a sugar pill. people will take the pill and sin...~*¤DaL!a¤*~So I know what a double blind study is but what is a single study?~*¤DaL!a¤*~A double-blind is where neither the participants nor the researchers know who is in what condition of the study (i.e., who is taking a placebo and who is taking the real drug). A single-blind is wh...Dark AAre blind and double blind primarily used to prevent intentional cheating?Dark ANo, they are used to prevent bias. As hard as we try, often in experiments our own experiences in life enter into out judgment when determining results of experiments. Blind, double blind and triple b...A guy from AnnistonWhat kind of jig is needed for a double blind mitered dovetail joint?A guy from AnnistonGo to one of these websites and peruse the threads or even join up and ask the questions: http://www.woodworkingtalk.com/ http://www.sawmillcreek.org/index.php There are some very experienced p...
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