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Anti-diabetic drugs treat diabetes mellitus by lowering glucose levels in the blood. With the exceptions of insulin, exenatide, and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral antihyperglycemic agents. There are different classes of anti-diabetic drugs, and their selection depends on the nature of the diabetes, age and situation of the person, as well as other factors.

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Wikipedia About Diabetes Drugs

Anti-diabetic drugs treat diabetes mellitus by lowering glucose levels in the blood. With the exceptions of insulin, exenatide, and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral antihyperglycemic agents. There are different classes of anti-diabetic drugs, and their selection depends on the nature of the diabetes, age and situation of the person, as well as other factors.

Diabetes mellitus type 1 is a disease caused by the lack of insulin. Insulin must be used in Type I, which must be injected or inhaled.

Diabetes mellitus type 2 is a disease of insulin resistance by cells. Treatments include (1) agents which increase the amount of insulin secreted by the pancreas, (2) agents which increase the sensitivity of target organs to insulin, and (3) agents which decrease the rate at which glucose is absorbed from the gastrointestinal tract.

Several groups of drugs, mostly given by mouth, are effective in Type II, often in combination. The therapeutic combination in Type II may include insulin, not necessarily because oral agents have failed completely, but in search of a desired combination of effects. The great advantage of injected insulin in Type II is that a well-educated patient can adjust the dose, or even take additional doses, when blood glucose levels measured by the patient, usually with a simple meter, as needed by the measured amount of sugar in the blood.

Insulin

main: insulin

Insulin is usually given subcutaneously, either by injections or by an insulin pump. Research is underway of other routes of administration. In acute care settings, insulin may also be given intravenously. There are several types of insulin, characterized by the rate which they are metabolized by the body.

Sulfonylureas

main: Sulfonylurea Sulfonylureas were the first widely used oral hypoglycemic medications. They are insulin secretagogues, triggering insulin release by direct action on the KATP channel of the pancreatic beta cells. Eight types of these pills have been marketed in North America, but not all remain available. The "second-generation" drugs are now more commonly used. They are more effective than first-generation drugs and have fewer side effects. All may cause weight gain.

Sulfonylureas bind strongly to plasma proteins. Sulfonylureas are only useful in Type II diabetes, as they work by stimulating endogenous release of insulin. They work best with patients over 40 years old, who have had diabetes mellitus for under ten years. They can not be used with type I diabetes, or diabetes of pregnancy. They can be safely used with metformin or -glitazones. The primary side effect is hypoglycemia.

  • First-generation agents
  • tolbutamide (Orinase)
  • acetohexamide (Dymelor)
  • tolazamide (Tolinase)
  • chlorpropamide (Diabinese)
  • Second-generation agents
  • glipizide (Glucotrol)
  • glyburide (Diabeta, Micronase, Glynase)
  • glimepiride (Amaryl)
  • gliclazide (Diamicron)

Search results for Diabetes Drugs

Metformin vs. Avandia: Are older diabetes drugs more effective ...

Metformin? Avandia? Other diabetes drugs? A Mayo Clinic specialist helps you weigh the options. ... Various diabetes drugs work in different ways to lower ...www.mayoclinic.com/health/metformin/DA00141

Diabetes Drugs

For people with diabetes, drugs such as glyburide, metformin, and insulin can ... Diabetes Health Topics. Disease & Conditions. Tests & Procedures. Drugs ...diabetes.emedtv.com/diabetes/diabetes-drugs.html

Old Diabetes Drug Has Advantages

The generic diabetes drug metformin is just as effective as newer, pricier diabetes drugs, but it has fewer troubling side effects, a new report suggests.diabetes.webmd.com/news/20070716/old-diabetes-drug-has-advan...

Diabetes Drugs Compared

A new study comparing three major diabetes drugs -- Avandia, Glucophage (metformin), and Micronase (glyburide) -- shows that all three drugs have pros and cons to ...diabetes.webmd.com/news/20061206/diabetes-drugs-compared

Diabetes Information from Drugs.com

Diabetes is a life-long disease marked by high levels of sugar in the blood. ... Veterinary Drugs. News Feeds. Drugs by Condition. Diabetes ...www.drugs.com/diabetes.html

Images found for Diabetes Drugs

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News about Diabetes Drugs

UA spinoff seeks safer cancer drugs

Arizona Daily StarA University of Arizona spinoff company started by a husband-and-wife team is marketing a new technology aimed at making cancer drugs safer.http://www.azstarnet.com/sn/business/291822.php

Gilead Sciences relies on CV Therapeutics, other deals to expand

Pioneer PressThe biotech company makes most of its money from its anti-AIDS drugs, but has been snapping up other companies to expand its lineup.http://www.twincities.com/outdoors/ci_11909008?source=rss

Popular diabetes treatment could trigger pancreatitis, pancreatic cancer

UC NewsroomDrug's adverse effects negated when combined with older diabetes drug.http://www.universityofcalifornia.edu/news/article/21079

Amylin seeks FDA OK on once-weekly diabetes drug

AP via Yahoo! NewsBiotechnology company Amylin Pharmaceuticals Inc. said Tuesday it asked the Food and Drug Administration to approve its highly anticipated once-weekly injectable diabetes treatment exenatide LAR.http://news.yahoo.com/s/ap/20090505/ap_on_bi_ge/us_amylin_fd...

Pittsburgh Street Dealer Roundup Finds Drugs, Toy Guns

WTAE-TV PittsburghPittsburgh police have rounded up 10 street-level drug dealers, seizing cash, heroin and weapons -- including three toy guns that look real and were apparently being used by the dealers as "protection."http://www.thepittsburghchannel.com/news/19404989/detail.htm...

News about Diabetes Drugs

Beating diabetes - Association to look at whether control equals 'cure ...

MissoulianThe 50-year-old Boston woman was able to avoid diabetes drugs through diet and exercise, managing to trim 40 pounds off her 5-foot-2 frame. “It is about willpower. That’s how you make the changes,” said Stern. Even diabetics who have resorted to ... http://www.missoulian.com/articles/2009/05/05/health/health2...

China's Bad Medicine

Wall Street JournalChina has had more than its share of embarrassing -- and in some cases, deadly -- incidents of drug quality. In January this year, two people died and nine were hospitalized after using counterfeit diabetes drugs in Xinjiang province. In 2007 and ... http://online.wsj.com/article/SB124146383501884323.html

FDA backs drug that treats diabetes via the brain

Atlanta Journal ConstitutionWASHINGTON — People with Type 2 diabetes may soon get a very different treatment approach: A drug that helps control blood sugar via the brain — an idea sparked, surprisingly, by the metabolism of migrating birds. The Food and Drug Administration ... http://www.ajc.com/health/content/health/stories/2009/05/07/...

Diabetes care: Employers save money after lowering costs for employees ...

Chicago TribuneChicago employers lowered costs for their workers with diabetes by more than $1,400 per employee over a year's time thanks to an experimental program that helped pay for their drugs and provided consultations at the pharmacy counter. Direct and ... http://www.chicagotribune.com/business/chi-thu-notebook-diab...

Drug maker announces new facility in Mass.

Boston GlobeNovartis already has about 2,000 employees split among several facilities in the city, where scientists are developing cancer and diabetes drugs. ----- ... http://www.boston.com/news/education/higher/articles/2009/05...

Search results for Diabetes Drugs

Diabetes Drug Report -- News about diabetes drugs

A report of latest news and reviews about prescription and non-prescription diabetes drugs, including Byetta, Januvia, Galvus, metformin, Avandia and Actos, as well as other ... http://www.diabetesdrugreport.com/

Other Medications for Type 2 Diabetes - American Diabetes Association

However, hypoglycemia can occur when acarbose or meglitol is taken in combination with other oral diabetes medications. Two new injectable drugs have recently been approved by the ... http://www.diabetes.org/type-2-diabetes/oral-medications.jsp

Diabetes News - American Diabetes Association

FDA raises the bar for new diabetes drugs. WASHINGTON - New drugs to treat an epidemic of diabetes will have to be screened more closely for heart risks, federal health officials ... http://www.diabetes.org/diabetesnewsarticle.jsp?storyId=1910...

Common Diabetes Drugs

The experts at WebMD provide a list of common diabetes drugs.http://diabetes.webmd.com/diabetes-medications

Diabetes Drugs Compared

A new study comparing three major diabetes drugs -- Avandia, Glucophage (metformin), and Micronase (glyburide) -- shows that all three drugs have pros and cons to consider.http://diabetes.webmd.com/news/20061206/diabetes-drugs-compa...

Wikipedia results for Diabetes Drugs

Anti-diabetic drug - Wikipedia, the free encyclopedia

Anti-diabetic drugs treat diabetes mellitus by lowering glucose levels in the blood. With the exceptions of insulin, exenatide, and pramlintide, all are administered orally and are ... http://en.wikipedia.org/wiki/Antidiabetic_drugs

Diabetes management - Wikipedia, the free encyclopedia

... works better than the diet recommended by the American Diabetes Association in controlling diabetes, and may control blood sugar levels with the same efficacy as oral diabetes drugshttp://en.wikipedia.org/wiki/index.html?curid=2966520

Diabetes mellitus - Wikipedia, the free encyclopedia

There are numerous studies which suggest connections between some aspects of Type II diabetes with ingestion of certain foods or with some drugs.http://en.wikipedia.org/wiki/Diabetes_melitus

Diabetes mellitus type 2 - Wikipedia, the free encyclopedia

One of the most widely used drugs now used for type 2 diabetes is the biguanide metformin; it works primarily by reducing liver release of blood glucose from glycogen stores and ... http://en.wikipedia.org/wiki/Diabetes_type_2

Diabetic diet - Wikipedia, the free encyclopedia

They may confer no special benefits to people who suffer from diabetes. Alcohol and drugs. Moderation is advised with regards to consuming alcohol and the use of some drugs.http://en.wikipedia.org/wiki/Diabetic_diet
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Videos found for Diabetes

Survey Shows Millions Don't Know Th...

Survey Shows Millions Don't Know They're DiabeticA new survey reveals that six million Americans have undiagnosed diabetes. David Gonzales reports.Windows Media - Video

Jason Statham in "Diabetes"

Jason Statham in A sweet summer blockbuster guaranteed to get your blood sugar level rising. See more at collegehumor.com/originals or check us out on the go at our mobile site.Flash - Video

Diabetic diet takes planning

Diabetic diet takes planningMeal planning can one of the most difficult parts of living with diabetes as CNN's Judy Fortin reports.Windows Media - Video

Living with Type 1 Diabetes

Living with Type 1 DiabetesFive-year-old Merrill Eastman addresses common misconceptions about diabetes.Flash - Video

Diabetes Drug Milestone

Diabetes Drug MilestoneA first-of-its-kind diabetes drug has a trio of biopharma stocks moving higher today, with CNBC's Mike Huckman.Flash - Video

Answers for Diabetes Drugs

Skittl3sWhat are the most effective drugs in treating type 2 diabetes?Skittl3sthe doctor will suit a drug for each individual according to his history with type 2 diabetes and his concomitant disease ORAL HYPOGLYCEMIC DRUGS Thomas Higgins, M.D. Oral hypoglycemic dru...penabriDoes anyone know where I could get market share percentages of all type 2 diabetes drugs?penabrinoRichMWhat effect do illegal drugs have upon diabetes type 1 (insulin)?RichMa lot of them effect your brain and don't effect other organs/ insulin. I'm sure if you ate weed brownies though that would effect it.ANEVCan the type two diabetes drug Metformin cure insulin resistance?ANEVMetformin cannot "cure" insulin resistance. All body cells need glucose to functon. However, the glucose molecule is too large to pass through the cell wall. In order to allow the glucose to pass ...sagar cWhat are the therapeutic drugs used to treat diabetes,meningitis,kidney infection and tuberculosis?sagar c
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