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Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid hormones. It acts as an anti-inflammatory and immunosuppressant. Its potency is about 20-30 times that of hydrocortisone and 4-5 times of prednisone.

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Blogs for Dexamethasone

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Posts tagged Dexamethasone at The Cancer Blog

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stephenlue9's Blog on Flixya

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Wikipedia About Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid hormones. It acts as an anti-inflammatory and immunosuppressant. Its potency is about 20-30 times that of hydrocortisone and 4-5 times of prednisone.

Anti-inflammatory

Dexamethasone is used to treat many inflammatory and autoimmune conditions, e.g., rheumatoid arthritis.

It is also given in small amounts (usually 5-6 tablets) before and/or after some forms of dental surgery, such as the extraction of the wisdom teeth, an operation which often leaves the patient with puffy, swollen cheeks.

It is injected into the heel when treating plantar fasciitis, sometimes in conjunction with triamcinolone acetonide.

It is useful to counteract allergic anaphylactic shock, if given in high doses. It is present in certain eye drops and as a nasal spray (trade name Dexacort).

Dexamethasone is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium. The steroid is released into the myocardium as soon as the screw is extended and can play a significant role in minimizing the acute pacing threshold due to the reduction of inflammatory response. The typical quantity present in a lead tip is less than 1.0 mg.

Dexamethasone is often administered before antibiotics in cases of bacterial meningitis. It then acts to reduce the inflammatory response of the body to the bacteria killed by the antibiotics (bacterial death releases pro-inflammatory mediators that can cause a response which is harmful to the patient), thus improving prognosis and outcome.

Oncologic uses

In oncology, it is given to cancer patients undergoing chemotherapy, to counteract certain side-effects of their antitumor treatment. Dexamethasone can augment the antiemetic effect of 5-HT3 receptor antagonists like ondansetron. Dexamethasone is also used in certain hematological malignancies, especially in the treatment of multiple myeloma, in which dexamethasone is given alone or together with thalidomide (thal-dex) or a combination of Adriamycin (doxorubicin) and vincristine (VAD). In brain tumours (primary or metastatic), dexamethasone is used to counteract the development of edema, which could eventually compress other brain structures. Dexamethasone is also given in cord compression where a tumor is compressing the spinal cord.

Endocrine

Dexamethasone can be used in the context of congenital adrenal hyperplasia, to prevent virilisation of a female fetus. If one or both parents are carriers of mutations to the CYP21 (CYP21A2) gene, the mother may start dexamethasone treatment within 7 weeks of conception. At the 12th week, a chorionic villus sample will determine whether the fetus is male (in which case the dexamethasone is stopped) or female. Subsequent DNA analysis can then reveal whether the female fetus is a carrier of the mutation, in which case dexamethasone treatment must continue until birth. The side-effects for the mother can be severe and the long-term impact on the child is not clear.

Search results for Dexamethasone

Dexamethasone Information on Healthline

Dexamethasone is a synthetic glucocorticoid. Its naturally occuring counterparts are ... Dexamethasone may also be called by its brand name, Decadron, and is ...www.healthline.com/galecontent/dexamethasone

Dexamethasone, Decadron, Dexasone, Diodex, Hexadrol, Maxidex ...

Dexamethasone has many uses in the treatment of cancer. ... Decadron is the trade name for dexamethasone. ... Dexamethasone relieves inflammation in various ...www.chemocare.com/bio/dexamethasone.asp

Dexamethasone

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Patient Education - Drugs - dexamethasone

Jackson Gastroenterology's Web Site includes office information and paient ... Dexamethasone is used to treat a wide range of disorders such as asthma and arthritis. ...www.gicare.com/pated/dexamethasone.htm

Decadron (Dexamethasone) drug description - FDA approved labeling for ...

Find Decadron (Dexamethasone) medication description and FDA approved drug information including side effects, interactions and patient labeling.www.rxlist.com/cgi/generic/dexameth.htm

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Best of ExplorersWeb 2008 Awards: Spirit of mountaineering, Inaki Ochoa's rescue team

MountEverest.net04:07 pm CST Dec 30, 2008 Let us tell you a story about true mountaineering. When Iñaki Ochoa de Olza became ill at 7400 meters; a tattered crew of mountaineers rushed to his aid. Feet frozen and bodies worn from recent climbs, they attacked Annapurna's deadly south wall as if it were a hiking peak.http://www.mounteverest.net/news.php?id=17920

Facet Biotech Reports First Quarter 2009 Financial Results

Marketwire$20 Million Cash Utilization for the First Quarter 2009http://www.marketwire.com/mw/release.do?id=984884&sourceType...

Array BioPharma Reports Financial Results for the Third Quarter of Fiscal 2009

Business Wire via Yahoo! FinanceBOULDER, Colo.----Array BioPharma Inc. today reported financial results for the third quarter ended March 31, 2009.http://biz.yahoo.com/bw/090504/20090504005927.html?.v=1

News about Dexamethasone

Asthma Meds Don't Work as Well in Overweight Patients

MedicineNet.comWe took blood cells and airway cells" from all, he said, and measured the response of the cells to the glucocorticoid called dexamethasone. The steroid works by interfering with inflammatory signaling pathways by raising the level of a molecule called ... http://www.medicinenet.com/script/main/art.asp?articlekey=93...

Viewpoints Index

Medscape NewsDexamethasone for Children After Tonsillectomy? Does the potential increased risk for bleeding raise concerns about routine use of the drug? Experts And Viewpoints, April 2009 Children Taken to Emergency Department for Nonurgent Conditions Efforts to ... http://www.medscape.com/index/section_2913_0

New Drug May Work Better Against Chemo Side Effects

MedicineNet.comIn the phase III trial, about three-fourths of the people given either drug (both given in combination with dexamethasone) did not experience nausea and vomiting in the 24 hours immediately after receiving a chemotherapy regimen that included drugs ... http://www.medicinenet.com/script/main/art.asp?articlekey=95...

National Institute For Health And Clinical Excellence Offers Treatment ...

Medical News TodayThe National Institute for Health and Clinical Excellence (NICE) has issued its final appraisal determination (FAD) recommending the use of Revlimid (lenalidomide) in combination with dexamethasone for the treatment of multiple myeloma in patients ... http://www.medicalnewstoday.com/articles/147334.php

Refer to a friend

PR InsideCelgene International Sàrl (Nasdaq:CELG) today announced that the National Institute for Health and Clinical Excellence (NICE) has issued a Final Appraisal Determination (FAD) recommending REVLIMID, in combination with dexamethasone, within its ... http://www.pr-inside.com/revlimid-receives-positive-final-ap...

Search results for Dexamethasone

dexamethasone: Definition from Answers.com

dexamethasone ( ) n. A synthetic glucocorticoid used primarily in the treatment of inflammatory disordershttp://www.answers.com/topic/dexamethasone

Dexamethasone For Veterinary Use

Therapeutic Class Adrenocorticosteroid hormone: Species Dogs, Cats, Horses: Commonly prescribed by vets for: Anti-inflammatory http://www.wedgewoodpharmacy.com/monographs/dexamethasone2.a...

Dexamethasone Side Effects | Drugs.com

Comprehensive and accurate Dexamethasone side effects information for consumers and healthcare professionals.http://www.drugs.com/sfx/dexamethasone-side-effects.html

Dexamethasone suppression test - Wikipedia, the free encyclopedia

The dexamethasone suppression test is designed to diagnose and differentiate among the various types of Cushing's syndrome and other hypercortisol states.http://en.wikipedia.org/wiki/Dexamethasone_suppression_test

Dexamethasone, Decadron, Dexasone, Diodex, Hexadrol, Maxidex ...

Dexamethasone has many uses in the treatment of cancer. It is classified as a glucocorticosteroid. Decadron, Dexasone, Diodex, Hexadrolhttp://www.chemocare.com/BIO/dexamethasone.asp

Wikipedia results for Dexamethasone

Dexamethasone - Wikipedia, the free encyclopedia

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid hormones. It acts as an anti-inflammatory and immunosuppressant.http://en.wikipedia.org/wiki/Dexamethasone

Dexamethasone suppression test - Wikipedia, the free encyclopedia

The dexamethasone suppression test is designed to diagnose and differentiate among the various types of Cushing's syndrome and other hypercortisol states.http://en.wikipedia.org/wiki/Dexamethasone_suppression_test

File:Dexamethasone.svg - Wikipedia, the free encyclopedia

Dexamethasone.svg ‎ (SVG file, nominally 1,461 × 1,069 pixels, file size: 20 KB)http://en.wikipedia.org/wiki/File:Dexamethasone.svg

RASD1 - Wikipedia, the free encyclopedia

RAS, dexamethasone-induced 1, also known as RASD1, is a human gene. [1] This gene encodes a Ras-related protein that is stimulated by dexamethasone.http://en.wikipedia.org/wiki/RASD1

TobraDex - Wikipedia, the free encyclopedia

TobraDex (tobramycin and dexamethasone ophthalmic suspension USP) is a prescription medication marketed in the United States by Alcon Labs. The active ingredients are tobramycin 0 ... http://en.wikipedia.org/wiki/TobraDex
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Answers for Dexamethasone

Gloria SCan Dexamethasone cause a diabetics sugar levels to rise?Gloria SYes, it can. It is shown that glucose intolerance is worsened & blood sugar levels are increased in patients with preexisting diabetes. Even those with latent or "inactive" diabetes manifest when they...DerekAfter predisone or dexamethasone treatment is stopped, how long does it take for your skin oils to return ?DerekIt depends of course on how long and how high a dose of Predisone you've been taking. My husband was on a large dose for several months and then 3 months weaning off - while he saw some side effects ...LoveeLoveGrlTaking a Dexamethasone suppression test tomorrow morning,question about taking the pill tonight?LoveeLoveGrlFollow your pharmacist and doctors instructions. One pill is probably not going to hurt anything (without food) and you need to be fasting for the blood work.derrickchristopherWhy is the drug dexamethasone - used in chemo- not combined with an appetite suppressant?derrickchristopherStevenIs dexamethasone effective for overactive adrenal / pituitary gland?StevenIs your endocrinologist using dexamethasone to treat you? I am a family medicine resident and I usually see dexamethasone used in people with adrenal insufficiency, which would be the opposite of ...
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