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Chitinase-1CNS.png

Chitinases are digestive enzymes that break down glycosidic bonds in chitin. Because chitin composes the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or to dissolve and digest the chitin of fungi or animals.

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Blogs for Chitinase

The Dish on Deliquescence in Coprinus Species :Cornell Mushroom Blog

Role of chitinase and other lysosomal enzymes of Coprinus lagopus in the ... Bane " Blog Archive " The Dish on Deliquescence in Coprinus Species on July 6th, ...blog.mycology.cornell.edu/?p=234

Connotea: Bookmarks matching tag chitinase

Blog. About Connotea. Site Guide. Community pages. Users who used chitinase: asa. aszat ... Chitinase B of "Microbulbifer degradans" 2-40 contains two ...www.connotea.org/tag/chitinase

Clipmarks - Chitinase Clipmarks

Connecting people with information. ... Sign Up Install Learn More Login. About Clippers Blog Privacy EULA Copyright Site Map. OK ...clipmarks.com/tags/chitinase/

IngentaConnect Antifungal activity of cucumber beta-1,3-glucanase and ...

Ingenta Blog. Help. Check our FAQs. Or contact us to report problems with: ... Chitinase A and B did not inhibit spore germination or fungal growth at the ...www.ingentaconnect.com/content/ap/pp/1996/00000049/00000004/...

IngentaConnect Induction of chitinase activity by exogenous cytokinins ...

Ingenta Blog. Help. Check our FAQs. Or contact us to report problems with: Subscription access ... K was totally ineffective in inducing chitinase activity. ...www.ingentaconnect.com/content/urban/271/2001/00000158/00000...

Wikipedia About Chitinase

Chitinase-1CNS.png

Chitinases are digestive enzymes that break down glycosidic bonds in chitin. Because chitin composes the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or to dissolve and digest the chitin of fungi or animals.

Species distribution

Chitinivorous organisms include many bacteria (Aeromonads, Bacillus, Vibrio, among others), which may be pathogenic or detritivorous. They may attack arthropods, zooplankton or fungi; or they may degrade the remains of these organisms.

Fungi, such as Coccidioides immitis, are known to possess chitinases. This may be related to their typical role as detritivores and also to their potential as arthropod pathogens.

Plants may seem an unusual source for chitinase, but some of the archetypical chitinases have been characterized from plants (barley seed chitinase: PDB: 1CNS, ). Some plant chitinases are members of the pathogenesis related (PR) proteins which are induced after systemic acquired resistance induction (biotic and abiotic). Expression is mediated by the NPR1 gene and the salicylic acid pathway, both involved in resisting fungal and insect attack. Some may be required for creating fungal symbioses.

Function

Chitin, like cellulose, has been thought of as abundant but difficult to digest. It is typically considered unavailable carbohydrate in animal diets, though certain fish can digest chitin to sugar; and dogma suggests that just as ruminants need bacteria to digest cellulose, chitin digestion would also require symbiosis and lengthy fermentations. As such, the discovery of animal, and particular mammalian and human chitinases is somewhat surprising. Actually, human chitinases appear in gastric juices. This is likely to be digestive chitinase, for catabolic activity.

Further, chitinase activity can be detected systemically in humans, in the blood. and possibly cartilage . This is related, as is plant chitinase activity, to inflammation/pathogen resistance. .

Clinical signficance

As such, it is unsurprisingly related to allergies. What is surprising, perhaps, is that asthma in particular has been linked to enhanced chitinase expression levels.

Search results for Chitinase

CS0980 Chitinase Assay Kit sufficient for 100 multiwell tests

CS0980 Chitinase Assay Kit sufficient for 100 multiwell tests The kit provides ... Chitinase catalyzes the hydrolytic cleavage of the β-14-glycoside bond present ...www.sigmaaldrich.com/catalog/search/ProductDetail/SIGMA/CS09...

Plasmodium falciparum chitinase (PfCHT1), Human Parasite Drug Targets ...

Inhibition of chitinase... Plasmodium falciparum chitinase (PfCHT1) is thought to have a role in parasite ... The chitinase activity of the initial load, ...www.neb.com/nebecomm/products_Intl/productP5208.asp

Onchocerca volvulus chitinase (OvCHT1), Human Parasite Drug Targets ...

... role of the chitinase is ... Onchocerca volvulus chitinase (OvCHT1) is expressed during ... Results: No chitinase activity was detected in the unbound or ...www.neb.com/nebecomm/products_Intl/productP5206.asp

Chitinase isoenzymes in near-isogenic wheat lines challenged with ...

Five different peaks with chitinase activity were detected in control plants (pI ... Indications are that chitinase may also be involved in the defence of wheat ...ejournal.sinica.edu.tw/bbas/content/1998/2/bot92-04.html

chitinase

... enzymes > hydrolases > glycosidases > O-glycoside hydrolases > chitinase ... Resources in chitinase: No resources available for this category. ...www.msue.msu.edu/kr/default.cfm?node_id=62980

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News about Chitinase

Researchers Find Gene Mutation That Increases Asthma Risk

MedicineNet.comYKL-40 is what's known as a chitinase-like protein, because it attaches itself to chitin, possibly alerting the body that chitins are present. But, Dickey pointed out that in the developed world, chitin infections simply aren't an issue any longer, so ... http://www.medicinenet.com/script/main/art.asp?articlekey=88...

Meta-analysis of genome-wide expression patterns associated with ...

BioMed CentralMeta-analyses confirmed previously reported genes and helped identify genes (e.g. Tomosyn, Chitinase 5, Adar, Innexin 2, Transferrin 1, Sick, Oatp26F) and Gene Ontology categories (e.g. purine nucleotide binding) not previously associated with ... http://www.biomedcentral.com/1471-2164/9/503/abstract

The Da Vinci Code Cheats and Hints III (PS2)

SoftpediaThe painting puzzle to get the dirt off is First Chitinase, then Dismutase, then Catalase. Puzzle 4: The six statue puzzle is Venus in the middle, Jupiter on the top, to the right of that Mars, to the right of that, Aeneas, to the right of that Cupid ... http://news.softpedia.com/news/The-Da-Vinci-Code-Cheats-and-...

Defensive Protein Linked to Asthma

MedicineNet.comChitinase and chitinase-like proteins are a highly effective protective response against worms, and for most of human history, we have been burdened with these parasites. An asthma-like response probably evolved to protect against worms. Now it ... http://www.medicinenet.com/script/main/art.asp?articlekey=85...

Search results for Chitinase

Chitinase 3-like 1 (cartilage glycoprotein-39), Homo sapiens - UniGene ...

A summary of the mRNA sequence representatives for a transcribed locus ... Comparison of sequences in UniGene with selected protein reference sequences.http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=382...

N. crassa: NCU03209 - chitinase 1 precursor - Neurospora crassa

Locus: NCU03209.3 Chromosome/Linkage Group: I Gene Symbol Synonymshttp://www.broad.mit.edu/annotation/genome/neurospora/GeneLo...

N. crassa: NCU04883 - chitinase 1 precursor - Neurospora crassa

Locus: NCU04883.3 Chromosome/Linkage Group: IV Gene Symbol Synonymshttp://www.broad.mit.edu/annotation/genome/neurospora/GeneLo...

Rice Community Annotation - Chitinase family protein precursor

Superfamily: Cysteine Rich Peptides: Contact: Kevin Silverstein: Organization: University of Minnesota: Source: Silverstein, K.A.T., Moskal, W.A., Jr., Wu, H., Underwood, B.A ... http://rice.plantbiology.msu.edu/ca/gene_fams/22_38.shtml

InterPro: IPR011583 Chitinase II

The European Bioinformatics Institute ... O-Glycosyl hydrolases EC:3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or ... http://www.ebi.ac.uk/interpro/IEntry?ac=IPR011583
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