The human main arteries, part of the circulatory system. The circulatory system is extremely important for sustaining life. Its proper functioning is responsible for the delivery of oxygen and nutrients to all cells, as well as the removal of carbon dioxide and waste products, maintenance of optimum pH, and the mobility of the elements, proteins and cells of the immune system. In developed countries, the two leading causes of death, myocardial infarction and stroke each may directly result from an arterial system that has been slowly and progressively compromised by years of deterioration. (See atherosclerosis).
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WSJ's Health Blog offers news and analysis on health and the business of health. ... The blog also includes contributions from other staffers at the Journal, WSJ.com ...blogs.wsj.com/health/2007/08/17/checkup-on-treatments-for-pu...The human main arteries, part of the circulatory system. The circulatory system is extremely important for sustaining life. Its proper functioning is responsible for the delivery of oxygen and nutrients to all cells, as well as the removal of carbon dioxide and waste products, maintenance of optimum pH, and the mobility of the elements, proteins and cells of the immune system. In developed countries, the two leading causes of death, myocardial infarction and stroke each may directly result from an arterial system that has been slowly and progressively compromised by years of deterioration. (See atherosclerosis).
Description
The arterial system is the higher-pressure portion of the circulatory system. Arterial pressure varies between the peak pressure during heart contraction, called the systolic pressure, and the minimum, or diastolic pressure between contractions, when the heart expands and refills. This pressure variation within the artery produces the pulse which is observable in any artery, and reflects heart activity. Arteries also aid the heart by pumping blood. Arteries carry oxygenated blood away from the heart except for pulmonary arteries.
Anatomy
The anatomy of arteries can be separated into gross anatomy, at the macroscopic level, and microscopic anatomy, which must be studied with the aid of a microscope.
Gross anatomy
The arterial system of the human body is divided into systemic arteries, carrying blood from the heart to the whole body, and pulmonary arteries, carrying blood from the heart to the lungs.
Systemic arteries
Systemic arteries are the arteries of the systemic circulation, which is the portion of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart.
Pulmonary arteries
Pulmonary arteries are the arteries of the pulmonary circulation, which is the portion of the cardiovascular system which carries deoxygenated blood away from the heart, to the lungs, and returns oxygenated blood back to the heart.
Anatomy of the arterial wall The outermost layer is known as the tunica externa formerly known as "tunica adventitia" and is composed of connective tissue. Inside this layer is the tunica media, or media, which is made up of smooth muscle cells and elastic tissue. The innermost layer, which is in direct contact with the flow of blood is the tunica intima, commonly called the intima. This layer is made up of mainly endothelial cells. The hollow internal cavity in which the blood flows is called the lumen.
Pulmonary arteries
The pulmonary arteries carry deoxygenated blood that has just returned from the body to the heart towards the lungs, where carbon dioxide is exchanged for oxygen.
Systemic arteries
Systemic arteries can be subdivided into two types; muscular and elastic; according to the relative compositions of elastic and muscle tissue in their tunica media as well as their size and the makeup of the internal and external elastic lamina. The larger arteries >1cm diameter are generally elastic and the smaller ones 0.1-10mm tend to be muscular. Systemic arteries deliver blood to the arterioles, and then to the capillaries, where nutrients and gasses are exchanged.


























