Evolution of genomic sequence inhomogeneity at mid-range scales
BioMed Central
Substitutions were grouped according to their fixation within human populations: fixed substitutions (from the human-chimp-macaca alignment), major SNPs (> 80% mutant allele frequency within humans), medium SNPs (20% - 80% mutant allele fre...
New and Exciting in PLoS this week [A Blog Around The Clock]
ScienceBlogs
Current Status of a Model System: The Gene Gp-9 and Its Association with Social Organization in Fire Ants : The Gp-9 gene in fire ants represents an important model system for studying the evolution of social organization in insects as well...
Complete Genomics reports low-cost sequencing of 3 human genomes
PhysOrg
Complete Genomics, a third-generation human genome sequencing company, today announced publication of a report in the journal Science describing its proprietary DNA sequencing platform, including analysis of sequence data from three complet...
Genetic 'breakthroughs' in medicine are often nothing of the sort
The Guardian
The paper reporting the study states: "Nine subjects from a cohort of 87 depression patients were found to carry the mutant allele. These findings suggest that deficiency in brain serotonin synthesis may be an important risk factor for depr...
WaferGen Names Christopher Sears, Ph.D., Architect of High-Value Molecular Diagnostics and Computational Biology ...
redOrbit
FREMONT, Calif., Nov. 5 /PRNewswire-FirstCall/ -- WaferGen Biosystems, Inc. (OTC Bulletin Board: WGBS), a leading developer of state-of-the-art genetic analysis systems, today announced that Christopher Sears, Ph.D. has joined the company's...
Immune System vs. Cancer
Scientist
We decided to intercross mice that had one allele of p53 and one allele of perforin knocked out to generate progeny with nine different genotypes (see graphic). It took more than 50 breeding pairs to generate hundreds of mice. We coded the ...
Moving towards a treatment for Alzheimer's
Israel 21c
We then generated a humanized mouse model of Alzheimer's, with a specific gene that was present in approximately 30 percent of our study group (HLA DR15 allele). Conceivably, those people that have this gene could receive the same vaccine w...
Yalies find genetic link to PTSD
Yale Daily News
The team found that individuals with the short allele of the gene, which resulted in lower production of the serotonin transporter protein, were more likely to develop PTSD. No one had previously examined the allele’s relation to PTSD at su...
Asthma Not Determined by Genetics Alone
Newswise
While progress has been made in identifying 39 genes potentially associated with asthma, the disease is complex, and its development is likely dependent upon both genetics and environmental exposures.
Voters give a resounding 'yes' to the Pickerington Public Library Levy
Delaware News
Advocates for the Pickerington Public Library levy celebrated a significant victory election night, Nov. 3. Unofficial final results from the Fairfield County Board of Elections indicated Issue 16 passed with a 61.6 percent "yes" vote. "The...
It Is Not Just Genes Alone But Environmental Factors Also Determine ...
Med India
In some cases, an allele (part of a gene) found to be a higher risk factor for allergic asthma in some individuals might be associated with less risk of developing asthma in others. Martinez has pinpointed the CD14 gene as one such example,...
Asthma associated with both genetics and environmental exposures
News-Medical-Net
While progress has been made in identifying genes associated with asthma, the disease is complex, and its development is likely dependent upon both genetics and environmental exposures, according to a leading expert presenting at the annual...