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N-Acetylglucosamine - Wikipedia, the free encyclopedia
N-Acetylglucosamine (N-Acetyl-D-Glucosamine, or GlcNAc, or NAG) is a monosaccharide derivative of glucose. Chemically it is an amide between glucosamine and acetic acid.
UDP-N-acetylglucosamine - Wikipedia, the free encyclopedia
UDP-N-acetylglucosamine or UDP-GlcNAc is a nucleotide sugar and a coenzyme in metabolism. It is used by glycosyltransferases to transfer N-acetylglucosamine residues to substrates.
Glycan-dependent signaling: O-linked N-acetylglucosamine -- HANOVER 15 ...
O-GlcNAc-modified proteins and cellular architecture Many cytosolic proteins have been identified as substrates for O-GlcNAc addition, as Fig. 1 demonstrates.
GlcNAc-6P Levels Modulate the Expression of Curli Fibers by ...
Curli are extracellular surface fibers that are produced by many members of the Enterobacteriaceae and contribute to biofilm formation. The environmental cues that promote biofilm ...
Proteomic Approaches to Analyze the Dynamic Relationships Between ...
O-GlcNAc may also be detected using a lectin, succinylated wheat germ agglutinin (sWGA), that recognizes terminal N-acetylglucosamine. Because sWGA binds any terminal O-GlcNAc ...
US 5272066 - Synthetic method for enhancing glycoprotein stability
Attachment of GlcNAc residues to the thiol groups of the cysteine residues of a nonglycosylated protein can be accomplished by treating the protein with a GlcNAc glycoside or ...
Department of Biological Chemistry - Johns Hopkins University
Importantly, raising O-GlcNAc levels post-injury is protective in models of ischemia reperfusion injury, suggesting that modulation of O-GlcNAc may lead to the development of ...
Protein ubiquitination is modulated by O-GlcNAc glycosylation ...
Protein ubiquitination is modulated by O-GlcNAc glycosylation Céline Guinez, Anne-Marie Mir, Vanessa Dehennaut, René Cacan, Anne Harduin-Lepers, Jean-Claude Michalski and ...
Elevated Expression of O-GlcNAc-Modified Proteins and O-GlcNAc ...
(Investigative Ophthalmology and Visual Science. 2003;44:3802-3809.) © 2003 by The Association for Research in Vision and Ophthalmology, Inc. DOI: 10.1167/iovs.03-0227
O-Linked N-Acetylglucosamine Proteomics of Postsynaptic Density ...
O-GlcNAc Modification of Proteins from Mouse Postsynaptic Density Preparations— Distinct classes of O-GlcNAc-modified proteins were observed in this study.
O-GlcNAc Western Blot Detection Kit
Introducing a Western blot chemiluminescent detection kit for O-GlcNAc modification! Glycosylation and phosphorylation are two of the most extensively studied post-translational ...
O-GlcNAc Modification Is an Endogenous Inhibitor of the Proteasome.
BioInfoBank Library :: O-GlcNAc Modification Is an Endogenous Inhibitor of the Proteasome. Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c ...
The O-GlcNAc Modification -- Essentials of Glycobiology -- NCBI ...
This chapter presents an overview of the dynamic modification of serine or threonine hydroxyl moieties on nuclear and cytoplasmic proteins by β-linked N-acetylglucosamine, termed ...
Mapping Sites of O-GlcNAc Modification Using Affinity Tags for Serine ...
Research Mapping Sites of O-GlcNAc Modification Using Affinity Tags for Serine and Threonine Post-translational Modifications * Lance Wells,, Keith Vosseller,, Robert N. Cole, ...
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N-Acetylglucosamine (N-acetyl-D-glucosamine, or GlcNAc, or NAG) is a monosaccharide derivative of glucose. It is an amide between glucosamine and acetic acid. It has a molecular formula of C8H15NO6, a molar mass of 221.21 g/mol, and it is significant in several biological systems.

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These recent articles mention GlcNAc
On The Road to a Fully Synthetic Heparin
Medagadget.com
We report the first chemoenzymatic synthesis of the stable isotope-enriched heparin from a uniformly labeled [13 C, 15 N]N-acetylheparosan (-GlcA(1,4)GlcNAc-) prepared from E. coli K5. Glycosaminoglycan (GAG) precursors and heparin were for...
Diabetes-Related Erectile Dysfunction Linked to Vascular Damage
Daily News Central
O-GlcNAc hinders this normal chain of events by inhibiting the activation of eNOS, consequently reducing the release of NO and preventing the smooth muscle in the penis from relaxing. Without this relaxation, there is no shear stress to sto...
Glucosamine-like Supplement Inhibits Multiple Sclerosis, Type 1 ...
Science Daily
In studies on mice, Dr. Michael Demetriou and colleagues with the UC Irvine Center for Immunology found that N-acetylglucosamine (GlcNAc), which is similar but more effective than the widely available glucosamine, inhibited the growth and f...
Novel link between excessive nutrient levels and insulin resistance
HULIQ.com
Since the amount of O-GlcNAc is directly tied to availability of glucose, lipids and other nutrients in the bloodstream, the researchers believe that the hexosamine pathway acts as fuel gauge, protecting the body’s cells against the toxic e...